- P-ISSN 1010-0695
- E-ISSN 2288-3339
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- P-ISSN1010-0695
- E-ISSN2288-3339
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Study on Pharmacological Activity of Sipjeondaebotang by Difference in Component Ratio between Astragali Radix and Cinnamomi Cortex
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2008, v.29 no.1, pp.156-166
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(2008). Study on Pharmacological Activity of Sipjeondaebotang by Difference in Component Ratio between Astragali Radix and Cinnamomi Cortex. Journal of Korean Medicine, 29(1), 156-166.
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Abstract
Objective:Pamooltang (PM) and Sipjeondaebotang (SC) are used in Korea to treat many diseases such as sterility, menstrual disorder, and general prostration. We made a comparative study of PM and SC which are different in component ratio between Astragalus membranaceus BUNGE (AC) and Cinnamomum cassia PRESL. (CC). Methods:Anti-oxidation was studied by 1.1.-diphenyl-2-picrylhydrazyl (DPPH) assay and anti-inflammation was investigated by prostaglandin E2 (PGE2) and nitric oxide (NO) inhibition assay. For immune response activities, this study used NO synthesis on RAW 264.7 cells and splenocyte proliferation. Results:The results showed that PM and SC components had no significant effect of anti-oxidation or anti-inflammation. However, we observed their effects upon inducible NO synthesis in Raw 264.7 cells. The SC2 stimulated NO synthesis 11.42±1.36 μM (control; 0.89±0.00 μM). PM and SC components had the effect of immune response which in a dose-dependent manner significantly induced the splenocyte proliferation. The splenocyte proliferation induced by SC2 was higher than others at the concentration of 1, 10, 100, 1000 and 2000 μg/ml. The SC8 was shown to up-regulate IgG, 100 μg/ml 3.3 times, 1000 μg/ml 2.6 times as a control. Conclusions:These results may have important implications for our understanding of the ratios of AC and CC in SC.
- keywords
- Sipjeondaebotang, Pamooltang, NO synthesis, splenocyte
Reference
1
1. 이상인,강효신. 십전대보탕의 투여방법이 빈혈된 가토의 RBC, Hemoglobin 및 Hematocrit치 변화에 미치는 영향. 대한한의학회지. 1977;14 (1):57-64.
2
2. 김길훤,신민규,김완희. 십전대보탕Extract 투여가 Rat의 성장 및 장기중량에 미치는 영향. 경희한의대논문집. 1978;1:101-104.
3
3. 신미향,노석선,김형탁. 십전대보탕(十全大補湯)이 생기(生肌)작용에 미치는 영향. 대한한의학회지. 1993;14(1):31-44.
4
4. 이충헌,정진홍,유동렬. 십전대보탕(十全大補湯)과 십전대보탕가미방(十全大補湯加味方)의 산후 (産後)활용에 대한 문헌적 고찰. 대전대학교 논문집. 1998;7(1):645-657.
5
5. 이형주,문석재. 십전대보탕가미방(十全大補湯加味方)이 항암화학요법제의 항종양효과 및 종양세포의 lysosomal enzymes에 미치는 영향. 한국전통의학지. 1997;7(2):116-123.
6
6. 윤재호,최승훈,안규석. 십전대보탕(十全大補湯)이 암전이 억제에 미치는 영향. 대한한방종양의학회지. 1998;4(1):131-146.
7
7. 고영권,유봉하,박동원,유기원. 십전대보탕(十全大補湯)이 CD4+ 및 CD8+ T세포수에 미치는 영향. 대한한방종양의학회지. 1998;4(1):111-129.
8
8. Kamiyama H, Takano S, Ishikawa E, Tsuboi K, And Matsumura A, Anti-angiogenic and Imm- unomodulatory Effect of the Herbal Medicine “Juzen-taiho-to” on Malignant Glioma. Biolo- gical & pharmaceutical bulletin. 2005; 28(11): 2111-2116.
9
9. 이경구,황대선,유영법,마진열,하혜경,신현규. 사군자탕, 사물탕, 팔물탕 및 십전대보탕의 처방 구성 및 용량 용법에 관한 연구, 대한한의학원전학회지. 2006;19(4);223-224.
10
10. 朱震亨. 丹溪醫集. 北京. 人民衛生出版社. 1993
11
11. 金·李東垣 外. 東垣十種醫書. 台北. 五州出版社. 1983.
12
12. 虞溥. 醫學正傳. 서울. 成輔社. 1986.
13
13. 龔廷賢. 增補萬病回春 影印本. 서울. 一中社. 1992.
14
14. 武之望. 濟陰綱目. 서울. 一中社. 1992.
15
15. 張景岳. 張氏景岳全書. 서울. 翰成社. 1983.
16
16. 孫思邈. 赤水玄珠全集. 中國. 海著易堂藏版. 1913.
17
17. 汪認庵. 醫方集解. 中國. 文光圖書有限公司. 1987.
18
18. 傳山. 國譯 傳靑主男女科. 서울. 大星文化社. 1983.
19
19. 葉桂 著. 嚴星橋 重校. 葉天士女科全書. 台北. 力行書局有限公司. 1981.
20
20. 葉桂. 國譯 葉天士女科. 서울. 大星文化社. 1983.
21
21. 許浚. 對譯 東醫寶鑑. 서울. 法人文化社. 1999.
22
22. 周命新. 醫門寶鑑. 서울. 一中社. 1991.
23
23. 黃度淵. 醫宗損益 上. 서울. 麗江出版社. 1993.
24
24. 黃度淵. 醫宗損益 下. 서울. 麗江出版社. 1993.
25
25. 黃度淵. 方藥合編. 서울. 麗江出版社. 1993.
26
26. 손재혁. 팔물탕이 생쥐 임신 말기에 면역세포의 cytokines 생성에 미치는 영향. 대한한방부인과학회지. 1999;12(2):341-374.
27
27. 허만규. 팔물탕이 알레르기 반응에 미치는 효과. 동의생리병리학회지. 2003;17(4):1075-1081.
28
28. Friedl R, Moeslinger T, Kopp B, and Spiecke- rmann PG. Stimulation of nitric oxide synthesis by the aqueous extract of Panax ginsena root in Raw 264.7 cells. British Journal of pharma- cology, 2001;134:1663-1670.
29
29. Farrell AJ, Blake DR. Nitric oxide. Annals of the Rheumatic Dieases. 1996;55:7-20.
30
30. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB Journal. 1992;6: 3051-3064.
31
31. Bingisser RM, Holt PG Immunomodulating mechanism in the lower respiratory tract; nitric oxide mediated intraction between alveolar macrophage, epithelial cell, and T-cell, SWISS Medical Weekly. 2001;131;171-179.
32
32. 신현규. 한방 처방의 Bio-informatics 구축 사업. 한국한의학연구원. 2007;59,75,111-112.
- Downloaded
- Viewed
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