Abstract

This study was designed to ascertain the characterist of cognitive function depend upon positive/negative symptoms of schizophrenia. Cognitive function was assessed with 6 KWIS subsets(information, comprehension, digit span, picture completion, block design, coding) and Grooved Pegboard Test, Trail Making Test, Wisconsin Card Sorting Test, Wechsler Memory Scale in patients with positive type(N=13) those with negative type(N=18) and neither type(N=11). Analysis was peformed by ANOVA, and followed by correlation analysis. According to the ANOVA results, the differences between 3 groups were significant in comprehension and block design, thus neither group showed the most superior results, and compared to the positive group, negative group showed significantly worst result. And in picture completion, coding, trail making, negative group of schizophrenia showed significant reduction in performance compared to nether group. Results from correlation analysis on total score of positive/negative symptom and cognitive function, positive symptom showed significant negative correlation in picture completion, pegboard test, negative symptom in comprehension, and block design, trail making test, wisconsin card sorting test, information and logical memory of wechsler memory test. On order to obtain more definite conclusion, we have to use standardized testing tools, as well as larger number of subjects with clear-cut positive or negative schizophrenic symptoms.