ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
 

  • P-ISSN2233-4203
  • E-ISSN2093-8950
  • ESCI, SCOPUS, KCI

논문 상세

Home > 논문 상세
  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Global Histidine Phosphoproteomics in Human Prostate Cancer Cells

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2020, v.11 no.3, pp.52-58
https://doi.org/10.5478/MSL.2020.11.3.52
Yan Gao (Kyungpook National University)
Doeun Kim (Kyungpook National University)
Eunji Sung (Kyungpook National University)
Minjia Tan (Kyungpook National University)
Tae Gyun Kwon (Kyungpook National University)
Jun Nyung Lee (Kyungpook National University)
Sangkyu Lee (Kyungpook National University)
  • 다운로드 수
  • 조회수

Abstract

Histidine phosphorylation (pHis) is increasingly recognized as an important post translational modification (PTM) in regulating cellular functions in eukaryotes. In order to clarify the role of pHis in mammalian cell signaling system, a global phos-phorylation study was performed in human prostate cancer cells, PC-3M, using a TiO 2 affinity chromatography. A total number of 307 pHis sites were identified on the 268 proteins among total identified 9,924 phosphorylation sites on 3,316 proteins. In addition, 22 pHis proteins were classified in enzyme category. This report provides the first database for the study of pHis in prostate cancer cells.

keywords
Histidine phosphorylation, TiO 2 -affinity chromatography, Mammalian cells, LC-MS


투고일Submission Date
2020-07-18
수정일Revised Date
2020-09-03
게재확정일Accepted Date
2020-09-03
상단으로 이동

Mass Spectrometry Letters