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  • P-ISSN2233-4203
  • E-ISSN2093-8950
  • ESCI, SCOPUS, KCI

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  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Amino-β-cyclodextrin Complex Assisted Ionization for Labile Sesamins and their Ion-mobility Separation in ESI Q-TOF MS

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2015, v.6 no.1, pp.17-20
https://doi.org/10.5478/MSL.2015.6.1.17
Kohtaro Sugahara (Suntory Institute for Bioorganic Research)
Manabu Horikawa (Suntory Institute for Bioorganic Research)
Tohru Yamagaki (Suntory Institute for Bioorganic Research)
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Abstract

Sesamin, one of the lignans in sesame seed, was a labile compound in MS and it was reported that the protonated moleculeof sesamin decomposed easily in ES ionization process and it cannot be detected (G. Yan, et al., Rapid Commun MassSpectrom. 2007, 21, 3613-3620). To protect labile compounds, an amino-cyclodextrin (NCyD) was added to the sample to promotethe host-guest interaction complex in ESI-MS. As a result, sesamin was ionized as the NCyD-sesamin-NCyD (1:2) complexwithout undesired decomposition, suggesting that the amino-CyDs assist the ionization of the labile molecules capped withCyDs by host-guest interaction and these compounds were ionized without their decomposition, those are like amino-CyD complex-assisted ionization. The amino-CyD complexes of sesamin and sesamolin were also analyzed by their ion-mobility MS.

keywords
cyclodextrin, host-guest interaction, ionization assist


참고문헌

1

Lin, C.-H.. (2014). . Plos One, 9, e96091-.

2

Deng, P.. (2013). . Biol. Pharm. Bull, 36, 1540-.

3

Akl, M. R.. (2012). . Planta Med, 78, 1731-.

4

Yan, G.. (2007). . Rapid Commun. Mass Spectrom, 21, 3613-.

5

Struijs, K.. (2008). . Rapid Commun. Mass Spectrom, 22, 3615-.

6

Yamaguchi, S.. (2008). . Korenaga T. Anal. Sci, 24, 1497-.

7

Yamagaki, T.. (2014). . J. Am. Soc. Mass Spectrom, 25, 95-.

8

Yamagaki, T.. (2009). . J. Mass Spectrom, 44, 1509-.

9

Yamagaki, T.. (2009). . Anal. Sci, 25, 985-.

투고일Submission Date
2014-12-01
수정일Revised Date
2015-02-17
게재확정일Accepted Date
2015-03-11
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Mass Spectrometry Letters