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  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Multi-class Analysis of Exposure Chemicals in Deciduous Teeth by Liquid Chromatography-Mass Spectrometry: Preliminary Studies on Sample Preparation Methods

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2018, v.9 no.4, pp.110-114
https://doi.org/10.5478/MSL.2018.9.4.110
Yujin Lee (Hankuk University of Foreign Studies)
Eunji Seo (Hankuk University of Foreign Studies)
Jun Young Park (Hankuk University of Foreign Studies)
Kwang-Hak Bae (Apple tree Dental Hospital)
Jaeick Lee (Korea Institute of Science and Technology,)
Sangwon Cha (Hankuk University of Foreign Studies)
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Abstract

Since accumulation of chemicals in deciduous teeth can occur from the second trimester of fetal development to shedding, a deciduous tooth has been considered as an attractive biomatrix for estimating individual chemical exposures recently. Therefore, detection of organic chemicals from teeth has received an increasing attention in exposomics research. Most previous studies on organic chemical analysis of teeth not only focused on a few targeted chemicals but also ignored potential contaminants from an enamel surface or a dental pulp. Recently, our group started developing a multi-class organic analysis method for deciduous teeth and tried to find a proper incubation condition of tooth materials. Our results showed that incubation with methanolic HCl provided the best performance among tested.

keywords
exposomics, deciduous teeth, sample preparation, dentin, enamel


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투고일Submission Date
2018-12-17
수정일Revised Date
2018-12-18
게재확정일Accepted Date
2018-12-18
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