E-ISSN : 2733-4538
This study investigated deficits of decision-making in college students with schizotypal traits using the Iowa Gambling Task (IGT) and the relationships between IGT and Wisconsin Card Sorting Test (WCST) performance. Based on scores of the Schizotypal Personality Questionnaire, schizotypal-trait (n=21) and normal control (n=21) groups were selected. In the IGT, the schizotypal-trait group showed lower total net-score and block net-scores in the final two blocks(4th and 5th), and selected B card more frequently than the normal control group. The control group showed increased block net-scores along with progressing blocks, whereas the schizotypal-trait group showed no increase of block net-scores. In the WCST, the schizotypal-trait group made more total errors and perseverative errors than the control group, and there was a significant negative correlation between perseverative errors of the WCST and the 4th block net-score of IGT in the schizotypal-trait group. Overall, these results indicate that college students with schizotypal traits have a deficit of decision-making, which may result from a perseverative tendency for the initially preferred option to persist, and deficits of decision-making can serve as markers of schizospectrum disorders.
강연욱 (1994). 누가 왼손잡이인가?: 한국인들의 손잡이 (HANDEDNESS) 평가. 한국심리학회지: 임상, 13, 97-113.
문희옥, 양익홍, 이홍표, 김묘은, 함 웅 (1997). 한국판 분열형 성격척도의 타당화 예비연구. 신경정신의학, 36, 329-343.
염태호, 박영숙, 오경자, 김정규, 이영호 (1992). K-WAIS 실시요강. 서울: 한국 가이던스.
전춘수, 김명선 (2010). 분열형 인격성향과 강박성향을 가진 여자대학생의 신경심리 프로파일 비교. 한국심리학회지: 임상, 29, 387-405.
한오수, 안준호, 송선희, 조맹제, 김장규, 배재남, 조성진, 정범수, 서동우, 함봉진, 이동우, 박종익, 홍진표 (2000). 한국어 판 구조화 임상면담도구 개발: 신뢰도 연구. 신경정신의학, 39, 362-372.
Bechara, A. (2007). Iowa gambling task professional manual. Lutz, FL: Psychological Assessment Resources.
Bechara, A., Tranel, D., & Damasio, H. (2000). Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesion. Brain, 123, 2189-2202.
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994). Insensitivity to future consequences following damage to human prefrontal cortex. Cognition, 50, 7-15.
Beninger, R. J., Wasserman, J., Zanibbi, K., Charbonneau, D., Mangels, J., & Beninger, B. V. (2003). Typical and atypical antipsychotic medications differentially affect two nondeclarative memory tasks in schizophrenic patients: a double dissociation. Schizophrenia Research, 61, 281-292.
Bowman, C. H, & Turnbull, O. H. (2009). Schizotypy and flexible learning: a prerequisite of creativity. Philoctetes, 2, 5-30.
Bozikas, V. P., Kosmidis, M. H., Kiosseoglou, G., & Karavatos, A. (2006). Neuropsychological profile of cognitively impaired patients with schizophrenia. Comprehensive Psychiatry, 47, 136-143.
Brand, M., Grabenhorst, F., Starcke, K., Vandekerckhove, M. M. P, & Markowitsch, H. J. (2007). Role of the amygdala in decisions under ambiguity and decisions under risk: evidence from patients with UrBach- Wiethe disease. Neuropsychologia, 45, 1305- 1317.
Cattapan-Ludewig, K., Ludewig, S., Messerli, N., Vollenweider, F. X., Seitz, A., Feldon, J., & Paulus, M. P. (2008). Decision-making dysregulation in first-episode schizophrenia. Journal of Nervous and Mental Disease, 196, 157-160.
Clark, L., Cools, R., & Robbins, T. W. (2004). The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning. Brain and Cognition, 55, 41-53
Demaree, H. A., Burns, K. J., & DeDonno, M. A. (2010). Intelligence, but not emotional intelligence, predicts Iowa Gambling Task performance. Intelligence, 38, 249-254.
Elliott, R., McKenna, P. J., Robbins, T. W., & Sahakian, B. J. (1995). Neuropsychological evidence for frontostriatal dysfunction in schizophrenia. Psychological Medicine, 25, 619-630.
Ernst, M., & Paulus, M. P. (2005). Neurobiology of decision making: a selective review from a neurocognitive and clinical perspective. Biological Psychiatry, 58, 597-604.
Evans, C. E. Y., Bowman, C. H., & Tumbull, O. H. (2005). Subjective awareness on the Iowa Gambling Task: the key role of emotional experience in schizophrenia. Journal of Clinical and Experimental Neuropsychology, 27, 656-664.
Fellows, L. K., & Farah, M. J. (2005). Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. Cerebral Cortex, 15, 58-63.
First, M. B., Spitzer, R. L., Gibbson, M., & Williams, J. B. W. (1996). Structured clinical Interview for DSM-Ⅳ Axis I disorder, research version, non-patient edition(SCID-Ⅰ/NP). New York: Biometrics Research, New York State Psychiatric Institute.
Garety, P. A., Hemsley, D. R., & Wessely, S. (1991). Reasoning in deluded schizophrenic and paranoid patients: biases in performance on a probabilistic inference task. Journal of Nervous and Mental Disease, 179, 194-201.
Gooding, D. C., Kwapil, T. R., & Tallent, K. A. (1999). Wisconsin Card Sorting Test deficits in schizotypic individuals. Schizophrenia Research, 40, 201-209.
Greve, K. W., Stickle, T. R., Love, J. M., Bianchini, K. J., & Stanford, M. S. (2005). Latent structure of the Wisconsin Card Sorting Test: a confirmatory factor analytic study. Archives of Clinical Neuropsychology, 20, 355-364.
Heaton, R. K., Chelune, G. J., Talley, J. L., Kay, G. G., & Curtiss, G. (1993). Wisconsin Card Sorting Test manual: revised and expanded. Odessa, FL: Psychological Assessment Resources.
Heaton, R. K. (1981). Wisconsin Card Sorting Test manual. Odessa, FL: Psychological Assessment Resources.
Heerey, E. A., Bell-Warren, K. R., & Gold, J. M. (2008). Decision-making impairments in the context of intact reward sensitivity in schizophrenia. Biological psychiatry, 64, 62-69.
Hutton, S. B., Murphy, F. C., Joyce, E. M., Rogers, R. D., Cuthbert, I., Barnes, T. R. E., McKenna, P. J., Sahakian, B. J., & Robbins T. W. (2002). Decision making deficits in patients with first-episode and chronic schizophrenia. Schizophrenia Research, 55, 249-257.
Kester, H. M., Sevy, S., Yechiam, E., Burdick, K. E., Cervellion, K. L., & Kumra, S. (2006). Decision-making impairments in adolescents with early-onset schizophrenia. Schizophrenia Research, 85, 113-123.
Kim, M. S., Oh, S. H., Hong, M. H., & Choi, D. B. (2011). Neuropsychologic profile of college students with schizotypal traits. Comprehensive Psychiatry, 52, 511-516.
Kim, M. S., Kang, S. S., Youn, T., Kang, D. H., Kim, J. J., & Kwon, J. S. (2003). Neuropsychological correlates of P300 abnormalities in patients with schizophrenia and obsessive-compulisve disorder. Psychiatry Research: Neuroimaging, 123, 109-123.
Kim, Y. T., Lee, K. U., & Lee, S. J. (2009). Deficit in decision-making in chronic, stable schizophrenia: from a reward and punishment perspective. Psychiatry Investigation 6, 26-33.
Lee, S. J., Lee, H. K., Kweon, Y. S., Lee, C. T., & Lee, K. U. (2009). The impact of executive function on emotion recognition and emotion experience in patients with schizophrenia. Psychiatry Investigation 6, 156-162.
Lee, Y., Kim, Y. T., Seo, E., Park, O., Jeong, S. H., Kim, S. H., & Lee, S. J. (2007). Dissociation of emotional decision-making from cognitive decision-making in chronic schizophrenia. Psychiatry Research, 152, 113-120.
Lin, H. F., Liu, Y. L., Liu, C. M., Hung, S. I., Hwu, H. G., & Chen, W. J. (2005). Neuregulin 1 gene and variations in perceptual aberration of schizotypal personality in adolescents. Psychological Medicine, 35, 1589-1598.
Maia, T. V., & McClelland, J. L. (2004). A reexamination of the evidence for the somatic marker hypothesis: what participants really know in the Iowa gambling task. Proceedings of the National Academy of Sciences of the United States of America, 101, 16075-16080.
Mitsogiannis, M. D. (2011). Developing translational animal models for decision making: the Iowa Gambling Task case. M. S. Dissertation, Universiteit Utrecht, Utrecht, Netherlands.
Moorhead, T. W. J., Stanfield, A., Spencer, M., Hall, J., McIntosh, A., Qwnes, D. C., Lawrie, S., & Johnstone, E. (2009). Progressive temporal lobe grey matter loss in adolescents with schizotypal traits and mild intellectual impairment. Psychiatry Research: Neuroimaging, 174, 105-109.
Morris, R. G., Rushe, T., Woodruffe, P. W. R., & Murray, R. M. (1995). Problem solving in schizophrenia: a specific deficit in planning ability. Schizophrenia Research, 14, 235-246.
Murray, G. K., Clark, L., Barnett, J. H., Blackwell, A. D., Fletcher, P. C., Robbins, T. W., Bullmore, C. T., & Jones, P. B. (2008). Reinforcement and reversal learning in first-episode psychosis. Schizophrenia Bulletin, 34, 848-855.
Nakamura, M., Nestor, P. G., Levitt, J. J., Cohen, A. S., Kawashima, T., Shenton, M. E., & McCarley, R. W. (2008). Orbitofrontal volume deficit in schizophrenia and thought disorder. Brain, 131, 180-195.
Noguchi, H., Hori, H. & Kunigi, H. (2008). Schizotypal traits and cognitive function in healthy adults. Psychiatry Research, 161, 162-169.
Polgár, P., Réthelyi, J. M., Bálint, S., Komlósi, S., Czobor, P., & Bitter, I. (2010). Executive function in deficit schizophrenia: what do the dimensions of the Wisconsin Card Sorting Test tell us?. Schizophrenia Research, 122, 85-93.
Premkumar, P., Fannon, D., Kuipers, E., Simmons. A., Frangou, S., & Kumari, V. (2008). Emotional decision-making and its dissociable components in schizophrenia and schizoaffective disorder; A behavioural and MRI investigation. Neuropsychologia, 46, 2002-2012.
Raine, A. (1991). The SPQ: a scale for the assessment of schizotypal personality based on DSM-Ⅲ-R criteria. Schizophrenia Bulletin, 17, 555-564.
Ritter, L. M., Meador-Woodruff, J. H., & Dalack, G. W. (2004). Neurocognitive measures of prefrontal cortical dysfunction in schizophrenia. Schizophrenia Research, 68, 65-73.
Rodríguez-Sánchez, J. M., Crespo-Facorro, B., Iglesias, R. P., Bosch, C. G., Álvarez, M., Llorca, J., & Vázquez-Barquero, J. L. (2005). Prefrontal cognitive functions in stabilized first-episode patients with schizophrenia spectrum disorders: a dissociation between dorsolateral and orbitofrontal functioning. Schizophrenia Research, 77, 279-288.
Shurman, B., Horan, W. P., & Nuechterlein, K. H. (2005). Schizophrenia patients demonstrate a distinctive pattern of decision-making impairment on the Iowa Gambling Task. Schizophrenia Research, 72, 215-224.
Siever, L. J. & Davis, K. L. (2004). The pathophysiology of schizophrenia disorders: perspectives from the spectrum. The American Journal of Psychiatry, 161, 398-413.
Struglia, F., Stratta, P., Gianfelice, D., Pacifico, R., Riccardi, I., & Rossi, A. (2011). Decision-making impairment in schizophrenia: relationships with positive symptomatology. Neuroscience letters. 502, 80-83.
Suhr, J. A. (1997). Executive functioning deficits in hypothetically psychosis-prone college students. Schizophrenia Research, 27, 29-35.
Suhr, J. A., & Spitznagel, M. B. (2001). Factor versus cluster models of schizotypal traits. Ⅱ: Relation to neuropsychological impairment. Schizophrenia Research, 52, 241-250.
Turnbull, O. H., Evans, C. E. Y., Kemish, K., & Park, S. (2006). A novel set-shifting modification of the Iowa Gambling Task: flexible emotion-based learning in schizophrenia. Neuropsychology, 20, 290-298.
Waltz, J. A., & Gold, J. M. (2007). Probabilistic reversal learning impairments in schizophrenia: further evidence of orbitofrontal dysfunction. Schizophrenia Research, 93, 296-303.
Wechsler, D. (1981). Manual for the Wechsler Adult Intelligence Scale-Revise. San Antonio, TX: Psychological Corporation.
Wilder, K. E., Weinberger, D. R., & Goldberg, T. E. (1998). Operant conditioning and the orbitofrontal cortex in schizophrenic patients: unexpected evidence for intact functioning. Schizophrenia research, 30, 169-174.
Wobrock, T., Ecker, U. K. H., Scherk, H., Schneider-Axmann, T., Falkai, P., & Gruber, O. (2009). Cognitive impairment of executive function as a core symptom of schizophrenia. World Journal of Biological Psychiatry, 10, 442-451.
Yip, S. W., Sacco, K. A., George, T. P., & Potenza, M. N. (2009). Risk/reward decision-making in schizophrenia: a preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance. Schizophrenia Research 110, 156-164.