ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
 

  • P-ISSN2233-4203
  • E-ISSN2093-8950
  • ESCI, SCOPUS, KCI

논문 상세

Home > 논문 상세
  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

A Simple Method for Determining Residual p-arsanilic Acid in Aquatic Products using EDTA-Assisted Solvent Extraction and LC-MRM

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2023, v.14 no.2, pp.36-41
https://doi.org/10.5478/MSL.2023.14.2.36
Min Kyeong Kwon (College of Pharmacy, Dankook University)
Ye Bin Shin (College of Pharmacy, Dankook University)
Young Min Kim (College of Pharmacy, Dankook University)
Jin Hwan Kim (College of Pharmacy, Dankook University)
Ji Seong Kim (College of Pharmacy, Dankook University)
Yong Seok Choi (College of Pharmacy, Dankook University)
  • 다운로드 수
  • 조회수

Abstract

A simple method was developed to determine residual p-arsanilic acid (ASA), an organo-arsenic compound used as a feed additive, in aquatic products (eel, halibut, and shrimp) using EDTA-assisted solvent extraction and LC-MRM. The method was successfully validated in terms of specificity, linearity (coefficient of determination ≥ 0.995), accuracy (recovery or R, 72.72-78.73%), precision (the relative standard deviation of R, 2.08-6.98%), and sensitivity (the lower limit of quantitation, 5 ppb) according to CODEX guidelines (CAC-GL 71-2009). The use of EDTA in the extraction solvent and water with a suitable pH modifier as the reconstitution solvent may be the key factors for successful results. This is the first method that can be used for monitoring residual ASA in aquatic products using LC-MRM and could contribute to establishing a better aquatic product safety management system.

keywords
p-arsanilic acid, MRM, EDTA, solvent extraction, halibut, eel, shrimp, aquatic products


투고일Submission Date
2023-06-16
수정일Revised Date
2023-06-23
게재확정일Accepted Date
2023-06-25
상단으로 이동

Mass Spectrometry Letters