Article Detail

Home > Article Detail
  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Peltier Heating-Assisted Low Temperature Plasma Ionization for Ambient Mass Spectrometry

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2015, v.6 no.3, pp.71-74
Lee Hyoung Jun (Korea Research Instiute of Standards and)
Oh Ji-Seon (Korea Research Instiute of Standards and)
Heo Sung Woo (Korea Research Instiute of Standards and)
Moon Jeong Hee (Korea Research Institute of Biology and)
Kim Jeong-hoon (Korea Research Institute of Biology and)
Park Sung Goo (Korea Research Institute of Biology and)
Park Byoung Chul (Korea Research Institute of Biology and)
Kweon Gi Ryang (Chungnam National University)
Yim Yong-Hyeon (Korea Research Institute of Standard and Science)
  • Downloaded
  • Viewed


Low temperature plasma (LTP) ionization mass spectrometry (MS) is one of the widely used ambient analysis methods which allows soft-ionization and rapid analysis of samples in ambient condition with minimal or no sample preparation. One of the major advantages of LTP MS is selective analysis of low-molecular weight, volatile and low- to medium-polarity analytes in a sam- ple. On the contrary, the selectivity for particular class of compound also implies its limitation in general analysis. One of the critical factors limiting LTP ionization efficiency is poor desorption of analytes with low volatility. In this study, a home-built LTP ioniza- tion source with Peltier heating sample stage was constructed to enhance desorption and ionization efficiencies of analytes in a sam- ple and its performance was evaluated using standard mixture containing fatty acid ethyl esters (FAEEs). It was also used to reproduce the previous bacterial identification experiment using pattern-recognition for FAEEs. Our result indicates, however, that the bacterial differentiation from FAEE pattern recognition using LTP ionization MS still has many limitations.

low temperature plasma ionization, Peltier heating, volatility, fatty acid ethyl ester



Takats, Z.. (2004). . Science, 306, 471-.


Cody, R. B.. (2005). . Anal. Chem, 77, 2297-.


Venter, A. R.. (2014). . Anal. Chem, 86, 233-.


Harper, J. D.. (2008). . Anal. Chem, 80, 9097-.


Salter, T. L.. (2014). . Anal. Chem, 86, 9264-.


Garcia-Reyes, J. F.. (2011). . Anal. Chem, 83, 1084-.


Chen, W. D.. (2013). . Analyst, 138, 5068-.


Zhang, J. I.. (2011). . Analyst, 136, 3091-.

Submission Date
Revised Date
Accepted Date
상단으로 이동

Mass Spectrometry Letters