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  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Analysis of Lipids in Deciduous Teeth by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI MS)

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2017, v.8 no.4, pp.105-108
https://doi.org/10.5478/MSL.2017.8.4.105
Yujin Lee (Hankuk University of Foreign Studies)
Eunji Seo (Hankuk University of Foreign Studies)
Tae-Min Park (Hankuk University of Foreign Studies)
Kwang-Hak Bae (Apple tree Dental Hospital)
Sangwon Cha (Hankuk University of Foreign Studies)
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Abstract

Recently, deciduous teeth have been proposed as a promising biomatrix for estimating internal and external chemical exposures of an individual from prenatal periods to early childhood. Therefore, detection of organic chemicals in teeth has received increasing attention. Organic materials in tooth matrix are mostly collagen type proteins, but lipids and other small organic chemicals are also present in the tooth matrix. In this study, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) was employed to obtain lipid fingerprints from deciduous teeth. Phospholipids and triacylglcerols (TAGs) from deciduous teeth were successfully detected by MALDI MS with 2,5-dihydroxybenzoic acid (DHB) or gold nanoparticle (AuNP) as a matrix.

keywords
deciduous teeth, MALDI, phospholipid, triacylglycerol, gold nanoparticle


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투고일Submission Date
2017-11-26
수정일Revised Date
2017-12-01
게재확정일Accepted Date
2017-12-01
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