- P-ISSN 2233-4203
- E-ISSN 2093-8950
- P-ISSN2233-4203
- E-ISSN2093-8950
- ESCI, SCOPUS, KCI
Article Detail
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Basics of Ion Mobility Mass Spectrometry
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2017, v.8 no.4, pp.79-89
https://doi.org/10.5478/MSL.2017.8.4.79
(Korea Research Institute of Standard and Science)
Lee,
J.
W.
(2017). Basics of Ion Mobility Mass Spectrometry. Mass Spectrometry Letters, 8(4), 79-89, https://doi.org/10.5478/MSL.2017.8.4.79
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Abstract
Ion mobility mass spectrometry (IM-MS) combines the advantages of ion mobility spectrometry (IMS) and MS for effective gas-phase ion analysis. Separation of ions based on their mobilities prior to MS can be performed without a great loss in other analytical figures of merit, and the extra dimension of analysis offered by IM can be beneficial for isomer and complex sample analyses. In this review, basic principles of IMS and IM-MS are described in addition to an introduction to various IMS techniques and commercial IM-MS instruments. The nature of collision cross-section (ΩD), an important parameter determining the transport properties of ions in IMS, is also explained in detail.
- keywords
- ion mobility spectrometry, ion mobility mass spectrometry, collision cross-section
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- Submission Date
- 2017-11-29
- Revised Date
- 2017-12-19
- Accepted Date
- 2017-12-19
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