Purpose: The purpose of this study is that the college age is an important transition period from youth to adulthood. Nursing students are unfamiliar with their field of study and need to adapt to a large amount of academic and practical training, so that they can have a better college life. An attempt was made to determine the effect of exam anxiety, academic stress, and alcohol dependence on the academic achievement of nursing students. Research design, data, and methodology: The subjects of the study were 130 students from all grades who agreed to participate in the study after expressing convenience among students attending the Department of Nursing at a university in Gyeongnam. The data collection period was from August 15 to September 15, 2023. It was about a month. The data investigation was conducted through a self-report survey. Results: Results showed that significant variables included exam anxiety, academic stress, alcohol dependency, parent relationships, peer relationships, and major satisfaction, explaining a total variance of 31.9%. Among these, the most influential factor was academic stress (β=-.352). Conclusions: This study identify factors influencing the academic achievement of nursing college students and hopes to contribute to formulating strategies for their growth and competence development.