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Differences in Memory between Dementia of the Alzheimer's type and Elderly depression

Abstract

The purpose of this study was to test differentiation of memory deficit in Alzheimer's disease group and depressive disorder group. Subjects were 24 mild Alzheimer-type dementia patiens(AD), 27 major depressive disorder patients(DEP), and 40 normal control group(NC). Finally 62 subject's output was analyzed. The memory test(K-MAS) was administered to 3 groups, all matched for sex, age, and educational level. AD group performed significantly worse than DEP, NC in most subtests of K-MAS. AD group showed (1) low total recall/recognition, (2) rapid rate of forgetting, (3) large numbers of intrusion, (4) recency part of serial position in free recall, (5) absence of practice effects. Discrimination analysis demonstrated 87.5% of diagnosis precision rate. Also, it was confirmed that Verbal Span test, Visual Span test, Delayed List Recall test, and Visual recognition have high discriminating power.

keywords
dementia of the Alzheimer's type, elderly depression, memory
Submission Date
2000-10-25
Revised Date
2001-07-04
Accepted Date
2001-09-11

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