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The Changes of Executive Function following Temporal Lobectomy in Temporal Lobe Epilepsy Patients

Abstract

This study examined the changes of executive function of the patients with temporal lobe epilepsy(TLE) after anterior temporal lobectomy(ATL) . According to the neural noise hypothesis, they were expected to show increase of executive function, especially those who have frontal dysfunction. In this study, 38 TLE patients were taken ATL and pre-post neuropsychological evaluation. The results were as follows: When all TLE patients were analyzed, there was no significant change in perseveration error, non-perseveration error nor any other indices of WCST. But when they were divided in two groups(frontal dysfunction group and intact group), there were significant interaction effects. Frontal dysfunction type patients showed significant decrease of perseverative error(p<.05) and significant increase of nonperseverative error(p<.05), but the other type patients showed no change. Findings and limitations of this study and suggestions for the further research were discussed

keywords
측두엽 간질, 실행기능, 전두엽 역기능, 측두엽 절제술, 위스콘신 카드 분류 검사, temporal lobe epilepsy, executive function, frontal dysfunction, temporal lobectomy, WCST

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