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Insomnia and depression are common to patients with obstructive sleep apnea syndrome (OSA). This study was conducted in order to explore the objective sleep characteristics, insomnia, and depressive symptoms of OSA and non-OSA patients and to provide clinical implications for diagnosis and treatment of OSA. A total of 145 patients (126 men, 19 women, average age: 49.56±12.06 years), who had been diagnosed as OSA, were administered polysomnography (PSG), the insomnia inventory, and the Beck Depression Inventory. The PSG showed that subjects in the OSA group had lower Sleep Efficiency (SE) and more difficulty in maintaining deep sleep than those in the non-OSA group. Although both the OSA and non-OSA groups had a significant level of insomnia and depressive symptoms, the non-OSA group showed more severe insomnia and depression than the OSA group. Correlation analysis was performed for identification of the significant indices of PSG relating to insomnia and depression. In the OSA group, patients who complained of more severe insomnia showed low SE and high Wakefulness After Sleep Onset (WASO). In addition, with greater depression, they showed high WASO and low Total Sleep Time (TST) and SE. However, in the non-OSA group, no correlation was observed between ISI or BDI and important sleep indices of PSG. Thus, for assessment of patients with OSA, it is necessary to examine not only physiological indices of the PSG but also the subjective clinical symptoms, such as insomnia and depression, so that we can anticipate problems that may occur during treatment and design tailored and efficient treatment plans.
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