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The effect of computerized executive function rehabilitation on the improvement of cognitive functions in patients with schizophrenia

Abstract

This study investigated the effect of executive rehabilitation on improvement of cognitive function in patients with schizophrenia. Thirty schizophrenia patients were randomly assigned to one of two groups, rehabilitation and control groups. Comprehensive neuropsychological tests including Wisconsin Card Sorting Test (WCST), Stroop test, Trail Making Test, Digit Span, Rey-Osterreith Complex Figure Test and Korea-California Verbal Learning Test were administered before and after rehabilitation for the two groups. In addition, schizophrenia symptoms and quality of life were measured using PANSS and SQLS, respectively. Participants in the rehabilitation group received executive rehabilitation three times a week for 6 weeks individually, whereas the control group did not receive rehabilitation. The two groups did not differ on the performances of any of the neuropsychological tests, PANSS and SQLS scores administered prior to rehabilitation training. The rehabilitation group showed significantly improved performances on the WCST (reduced total numbers of error and perseverative error) and Digit Span administered after the training. However, the control group did not show these improvements. These findings suggest that executive rehabilitation is effective for improvement of executive function and working memory in patients with schizophrenia.

keywords
신경심리검사, 인지기능, 위스콘신카드분류 검사, 전산화 집행 기능 재활, 조현병, neuropsychological test, cognitive function, computerized executive function rehabilitation, schizophrenia, WCST

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