- P-ISSN 2233-4203
- E-ISSN 2093-8950
- 권한신청
- P-ISSN2233-4203
- E-ISSN2093-8950
- ESCI, SCOPUS, KCI
논문 상세
Home > 논문 상세
Chiral Derivatization of Hydroxycarboxylic Acids Using 2,4,6-Trichlorobenzoyl Chloride as a Highly Efficient Regioselective Esterification Reagent for Gas Chromatography-Mass Spectrometry
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2020, v.11 no.4, pp.103-107
https://doi.org/10.5478/MSL.2020.11.4.103
(Department of Chemistry, Gachon University)
(Department of Chemistry, Gachon University)
(Department of Chemistry, Gachon University)
Park,
J. H.,
&
Han,
S.
Y.
(2020). . Mass Spectrometry Letters, 11(4), 103-107, https://doi.org/10.5478/MSL.2020.11.4.103
- 다운로드 수
- 조회수
Abstract
We report the application of 2,4,6-trichlorobenzoyl chloride (often referred to as Yamaguchi esterification reagent) for the selective derivatization of the carboxylic group for GC-MS with the sample preparation method optimized for GC-MS analysis. The reagent was shown to be capable of selectively turning the carboxylic group into a reaction center, i.e., anhydride, of which the further reaction was directed to a near complete formation of required esters by unique steric and electronic effects of the reagent. Using the developed method, the chiral separation of hydroxycarboxylic acids by GC-MS using non-chiral col-umns was successfully demonstrated.
- keywords
- 2, 4, 6-trichlorobenzoyl chloride, chiral separation, GC-MS, hydroxycarboxylic acids, O-acetylated L-menthyl esters
- 투고일Submission Date
- 2020-12-14
- 수정일Revised Date
- 2020-12-23
- 게재확정일Accepted Date
- 2020-12-23
권호 내 다른 논문
- Advances in Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS)-Based Techniques for Elucidating Higher-Order Protein Structures
- A Simple and Efficient Method to Determine Montelukast in Rat Plasma Using Liquid-Liquid Extraction and Tandem Mass Spectrometry
- Comparison of Matrices for Optimal Analysis of Synthetic Polymers Using MALDI-TOF Mass Spectrometry
- Simultaneous Determination of Anthraquinone, Flavonoids, and Phenolic Antidiabetic Compounds from Cassia auriculata Seeds by Validated UHPLC Based MS/MS Method
- Characterization of Natural Organic Matter in Spring Water
- A Low-Cost Open-Source Air Sampler for the Sorbent Tube Sampling for TD-GC/MS Analysis
- Chiral Derivatization of Hydroxycarboxylic Acids Using 2,4,6-Trichlorobenzoyl Chloride as a Highly Efficient Regioselective Esterification Reagent for Gas Chromatography-Mass Spectrometry
- Development of a Mushroom Powder Certified Reference Material for Element Analysis
- Inhibitory Potential of Bilobetin Against CYP2J2 Activities in Human Liver Microsomes
- Analysis of Hypoxia-Inducible Factor Stabilizers by a Modified QuEChERS Extraction for Antidoping Analysis
- more
추천 논문
학술지 홈페이지 이용 환경은 크롬 브라우저 사용을 권장합니다.