• P-ISSN2233-4203
  • E-ISSN2093-8950

Article Detail

Home > Article Detail
  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Comparison of Matrices for Optimal Analysis of Synthetic Polymers Using MALDI-TOF Mass Spectrometry

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2020, v.11 no.4, pp.78-81
Yoo Hee-Jin (Korea Basic Science Institute (KBSI))
Kim Duck-Hyun (Korea Basic Science Institute (KBSI))
Choi Yoon-Ji (Korea Basic Science Institute (KBSI))
Choi Jung Hoon (Korea Basic Science Institute (KBSI))
Park Moonhee (Korea Basic Science Institute (KBSI))
Shin DongJin (Korea Basic Science Institute (KBSI))
Oh YoonSeok (Korea Basic Science Institute (KBSI))
Kim YangSun (Korea Basic Science Institute (KBSI))
Cho Kun (Korea Basic Science Institute (KBSI))
  • Downloaded
  • Viewed


Characterization of the various chemical aspects of composite polymers is important for quality control of manufac-tured polymers. In this study, we compared three suitable matrices (α cyano-4-hydroxycinnamic acid [CHCA], 2,5 dihydroxy benzoic acid [2,5-DHB], and dithranol), to characterize various synthetic polymers by matrix-assisted laser desorption/ioniza-tion time-of-flight mass spectrometry. Although the spectra obtained with the CHCA and 2,5-DHB matrices were generally good, in certain samples ghost peaks disappeared only when dithranol was used as the matrix. Furthermore, we examined the use of sodium trifluoroacetate (NaTFA) as an additive to reduce interference by metals and copolymers in the spectra. In conclusion, appropriate selection of a matrix, according to the characteristics of the polymer, and the use of additives to improve sensitivity are important considerations for polymer analysis and development.

MALDI-TOF MS synthetic polymer CHCA 2 5-DHB dithranol

Submission Date
Revised Date
Accepted Date
상단으로 이동

Mass Spectrometry Letters