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  • P-ISSN2233-4203
  • E-ISSN2093-8950
  • ESCI, SCOPUS, KCI

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  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Observation of Peptide-Ion Generation by Laser-Induced Surface Heating from Tungsten Silicide Surfaces

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2012, v.3 no.1, pp.18-20
https://doi.org/10.5478/MSL.2012.3.1.018
Shin Hye Kim (Korea Research Institute of Standards and Science, Chungnam National University)
Sun Hwa Park (Korea Research Institute of Standards and Science,)
Jae Yong Song (Korea Research Institute of Standards and Science)
Sang Yun Han (Korea Research Institute of Standards and Science)
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Abstract

We report observation of laser desorption/ionization (LDI) of peptides from flat surfaces of tungsten silicide (WSi2). In contrast to MALDI (matrix-assisted laser desorption/ionization) and SALDI (surface-assisted laser desorption/ionization)mass spectrometry, this study did not utilize any matrices and surface nanostructures. In this work, LDI on WSi2 surfaces is demonstratedto cover a mass range up to 1,600 Da (somatostatin; monoisotopic mass = 1637.9 Da). In addition, it exhibited a high sensitivity, which could detect peptides, which could detect peptides of low femtomole levels (20 fmol for angiotensin II). The observed LDI process was discussed to be largely thermal, more specifically, due to laser-induced surface heating that is mostlikely promoted by the low thermal diffusivity (κ) of WSi2 substrate.

keywords
Laser desorption/ionization (LDI), Tungsten silicide (WSi2), Laser-induced surface heating


참고문헌

1

Peterson, D. S. (2007). . Mass Spectrom. Rev, 26, 19-.

2

Wei, J. (1999). . Nature, 399, 243-.

3

Alimpiev, S. (2001). . J. Chem. Phys, 115, 1891-.

4

Northen, T. R. (2007). . Nature, 449, 1033-.

5

Go, E. P. (2005). . Anal. Chem, 77, 1641-.

6

Walker, B. N. (2009). . Angew. Chem. Int. Ed, 48, 1669-.

7

Walker, B. N. (2010). . J. Phys. Chem. C, 114, 4835-.

8

Nayak, R. (2010). . Anal. Chem, 82, 7772-.

9

Seino, T. (2007). . Anal. Chem, 79, 4827-.

10

Shin, W. J. (2010). . J. Am. Soc. Mass Spectrom, 22, 989-.

11

Kim, S. H. (2012). . J. Am. Soc. Mass Spectrom, , -. http://dx.doi.org/10.1007/s13361-012-0355-5.

12

Hsu, N.-Y. (2008). . Anal. Chem, 80, 5203-.

13

Daves, Jr. G. D. (1979). . Acc. Chem. Res, 12, 359-.

투고일Submission Date
2012-02-27
수정일Revised Date
2012-03-06
게재확정일Accepted Date
2012-03-06
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Mass Spectrometry Letters