- P-ISSN 2233-4203
- E-ISSN 2093-8950
- P-ISSN2233-4203
- E-ISSN2093-8950
- ESCI, SCOPUS, KCI
논문 상세
Home > 논문 상세
Observation of Peptide-Ion Generation by Laser-Induced Surface Heating from Tungsten Silicide Surfaces
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2012, v.3 no.1, pp.18-20
https://doi.org/10.5478/MSL.2012.3.1.018
(Korea Research Institute of Standards and Science, Chungnam National University)
(Korea Research Institute of Standards and Science,)
(Korea Research Institute of Standards and Science)
(Korea Research Institute of Standards and Science)
(Korea Research Institute of Standards and Science,)
(Korea Research Institute of Standards and Science)
(Korea Research Institute of Standards and Science)
Kim,
S. H.,
Park,
S. H.,
Song,
J. Y.,
&
Han,
S.
Y.
(2012). . Mass Spectrometry Letters, 3(1), 18-20, https://doi.org/10.5478/MSL.2012.3.1.018
- 다운로드 수
- 조회수
Abstract
We report observation of laser desorption/ionization (LDI) of peptides from flat surfaces of tungsten silicide (WSi2). In contrast to MALDI (matrix-assisted laser desorption/ionization) and SALDI (surface-assisted laser desorption/ionization)mass spectrometry, this study did not utilize any matrices and surface nanostructures. In this work, LDI on WSi2 surfaces is demonstratedto cover a mass range up to 1,600 Da (somatostatin; monoisotopic mass = 1637.9 Da). In addition, it exhibited a high sensitivity, which could detect peptides, which could detect peptides of low femtomole levels (20 fmol for angiotensin II). The observed LDI process was discussed to be largely thermal, more specifically, due to laser-induced surface heating that is mostlikely promoted by the low thermal diffusivity (κ) of WSi2 substrate.
- keywords
- Laser desorption/ionization (LDI), Tungsten silicide (WSi2), Laser-induced surface heating
참고문헌
1
Peterson, D. S. (2007). . Mass Spectrom. Rev, 26, 19-.
2
Wei, J. (1999). . Nature, 399, 243-.
3
Alimpiev, S. (2001). . J. Chem. Phys, 115, 1891-.
4
Northen, T. R. (2007). . Nature, 449, 1033-.
5
Go, E. P. (2005). . Anal. Chem, 77, 1641-.
6
Walker, B. N. (2009). . Angew. Chem. Int. Ed, 48, 1669-.
7
Walker, B. N. (2010). . J. Phys. Chem. C, 114, 4835-.
8
Nayak, R. (2010). . Anal. Chem, 82, 7772-.
9
Seino, T. (2007). . Anal. Chem, 79, 4827-.
10
Shin, W. J. (2010). . J. Am. Soc. Mass Spectrom, 22, 989-.
11
12
Hsu, N.-Y. (2008). . Anal. Chem, 80, 5203-.
13
Daves, Jr. G. D. (1979). . Acc. Chem. Res, 12, 359-.
- 투고일Submission Date
- 2012-02-27
- 수정일Revised Date
- 2012-03-06
- 게재확정일Accepted Date
- 2012-03-06
권호 내 다른 논문
- Introduction of the Indian Society for Mass Spectrometry (ISMAS) (http:// www.ismas.org)
- Targeted Metabolite Profiling: Sample Preparation Techniques for GC-MS-Based Steroid Analysis
- Artificial Oxidation of Cysteine Residues in Peroxiredoxin 6 Detected by Twodimensional Gel Electrophoresis and Capillary Liquid Chromatography- Electrospray Mass Spectrometry
- Determination of the PDE-5 Inhibitors and Their Analogues by GC-MS and TMS Derivatization
- Observation of Peptide-Ion Generation by Laser-Induced Surface Heating from Tungsten Silicide Surfaces
- Comparative GC-MS Based In vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction
- Paint Spray Mass Spectrometry for the Detection of Additives from Polymers on Conducting Surfaces
- more
추천 논문
학술지 홈페이지 이용 환경은 크롬 브라우저 사용을 권장합니다.