- P-ISSN 2233-4203
- E-ISSN 2093-8950
- 권한신청
- P-ISSN2233-4203
- E-ISSN2093-8950
- ESCI
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Observation of Peptide-Ion Generation by Laser-Induced Surface Heating from Tungsten Silicide Surfaces
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2012, v.3 no.1, pp.18-20
https://doi.org/10.5478/MSL.2012.3.1.018
(Korea Research Institute of Standards and Science, Chungnam National University)
(Korea Research Institute of Standards and Science,)
(Korea Research Institute of Standards and Science)
(Korea Research Institute of Standards and Science)
(Korea Research Institute of Standards and Science,)
(Korea Research Institute of Standards and Science)
(Korea Research Institute of Standards and Science)
Kim,
S. H.,
Park,
S. H.,
Song,
J. Y.,
&
Han,
S.
Y.
(2012). . Mass Spectrometry Letters, 3(1), 18-20, https://doi.org/10.5478/MSL.2012.3.1.018
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Abstract
We report observation of laser desorption/ionization (LDI) of peptides from flat surfaces of tungsten silicide (WSi2). In contrast to MALDI (matrix-assisted laser desorption/ionization) and SALDI (surface-assisted laser desorption/ionization)mass spectrometry, this study did not utilize any matrices and surface nanostructures. In this work, LDI on WSi2 surfaces is demonstratedto cover a mass range up to 1,600 Da (somatostatin; monoisotopic mass = 1637.9 Da). In addition, it exhibited a high sensitivity, which could detect peptides, which could detect peptides of low femtomole levels (20 fmol for angiotensin II). The observed LDI process was discussed to be largely thermal, more specifically, due to laser-induced surface heating that is mostlikely promoted by the low thermal diffusivity (κ) of WSi2 substrate.
- keywords
- Laser desorption/ionization (LDI), Tungsten silicide (WSi2), Laser-induced surface heating
참고문헌
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- 투고일Submission Date
- 2012-02-27
- 수정일Revised Date
- 2012-03-06
- 게재확정일Accepted Date
- 2012-03-06
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