- P-ISSN 2233-4203
- E-ISSN 2093-8950
- 권한신청
- P-ISSN2233-4203
- E-ISSN2093-8950
- ESCI, SCOPUS, KCI
논문 상세
Home > 논문 상세
Diagnostic Evaluation of Enzyme Activity Related to Steroid Metabolism by Mass Spectrometry-Based Steroid Profiling
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2014, v.5 no.2, pp.35-41
https://doi.org/10.5478/MSL.2014.5.2.35
(Korea Institute of Science and Technology)
(Korea Institute of Science and Technology)
(Korea Institute of Science and Technology)
Cho,
M. H.,
&
Chung,
B.
C.
(2014). . Mass Spectrometry Letters, 5(2), 35-41, https://doi.org/10.5478/MSL.2014.5.2.35
- 다운로드 수
- 조회수
Abstract
Gas chromatography-mass spectrometry (GC-MS) methods have been used extensively in clinical steroid analyses. Evaluating the metabolic ratios of precursors to products by accurate quantification of individual steroid levels in biologicalsamples can reveal the activities of enzymes associated with steroid metabolism. This review article discusses the impact of GCMS-based steroid profiling on our understanding of the biochemical role of steroids and their metabolic enzymes in hormonedependentdiseases, such as congenital adrenal hyperplasia (CAH), cortisol-mediated hypertension, apparent mineralocorticoidexcess (AME), male-pattern baldness, and breast and thyroid cancers. Steroid profiling is a comprehensive analytical techniquethat can be applied whenever the highest specificity is required and may be a reasonable initial diagnostic approach.
- keywords
- steroid, metabolite profiling, biomarker, clinical diagnosis, steroidogenesis
참고문헌
1
Caulfield, M. P.. (2002). . J. Clin. Endocrinol. Metabol, 87, 3682-.
2
Minutti, C. Z.. (2004). . J. Clin. Endocrinol. Metabol, 89, 3687-.
3
White, P. C.. (1997). . Endo. Rev, 18, 135-.
4
Choi, M. H.. (2002). . Clin. Chim. Acta, 320, 95-.
5
Randall, V. A.. (1992). . J. Invest. Dermatol, 98, 86S-.
6
Choi, M. H.. (2001). . J. Invest. Dermatol, 116, 57-.
7
Baglietto, L.. (2010). . Cancer Epidemiol. Biomarkers Prev, 19, 492-.
8
Choi, M. H.. (2011). . J. BMC Cancer, 11, 342-.
9
Liu, W.. (2013). . J. Lipid Res, 54, 244-.
10
Son, H. H.. (2014). . J. Lipid Res, 55, 155-.
11
Moon, J. Y.. (2014). . J. Steroid Biochem. Mol. Biol, 141, 52-.
12
Kölsch, H.. (2004). . Neurosci. Lett, 368, 303-.
13
Shobob, L. A.. (2005). . Lancet Neurol, 4, 841-.
14
Karasinska, J. M.. (2011). . Nat. Rev. Neurol, 7, 561-.
15
Moon, J. Y.. (2009). . J. Am. Soc. Mass Spectrom, 20, 1626-.
16
Sharpe, L. J.. (2013). . J. Biol. Chem, 288, 18707-.
17
Xu, X.. (2007). . Nat. Protocol, 2, 1350-.
18
Cho, H. J.. (2009). . Anal. Chim. Acta, 632, 101-.
19
Riepe, F. G.. (2007). . Rev. Endocr. Metab. Disord, 8, 349-.
20
Wudy, S. A.. (1995). . Pediatr. Res, 38, 76-.
21
Wudy, S. A.. (2000). . Horm. Res, 53, 68-.
22
Lai, C. C.. (2002). . J. Clin. Lab Anal, 16, 20-.
23
Wong, T.. (1992). . Clin. Chem, 38, 1830-.
24
Kaddurah-Daouk, R.. (2008). . Annu. Rev. Pharmacol. Toxicol, 653, 48-.
25
Holst, J. P.. (2007). . Steroids, 72, 71-.
26
Sahin, Y.. (1997). . Eur. J. Endocrinol, 137, 670-.
27
Rauh, M.. (2009). . Mol. Cell. Endocrinol, 301, 272-.
28
Sun Ju Kim. (2011). Screening Analysis of 10 Adrenal Steroids by Matrix-Assisted Laser Desorption Ionization-Tandem Mass Spectrometry. Mass Spectrometry Letters, 2(3), 69-72.
29
Raff, H.. (1987). . Am. J. Physiol, 252, R635-.
30
Stewart, P. M.. (1996). . Lancet, 347, 88-.
31
Palermo, M.. (1996). . Clin. Endocrinol, 45, 605-.
32
Mantero, F.. (1996). . Steroids, 61, 193-.
33
Ferrari, P.. (2000). . Kideny Int, 57, 1374-.
34
Walker, B. R.. (1997). . J. Clin. Endocrinol. Metabol, 82, 4015-.
35
Sawaya, M.. (1991). . Ann. N. Y. Acad. Sci, 642, 376-.
36
Sinclair, R.. (1998). . Br. Med. J, 317, 865-.
37
Randall, V. A.. (1994). . Clin. Endocrinol, 40, 439-.
38
Sawaya, M. E.. (1997). . J. Invest. Dermatol, 109, 296-.
39
Hibberts, N. A.. (1998). . J. Endocrinol, 156, 59-.
40
Phillipou, G. Kirk. (1981). . J. Clin. Exp. Dermatol, 6, 53-.
41
Choi, M. H.. (1999). . Analyst, 124, 1297-.
42
Jung, H. J.. (2011). . Rapid Commun. Mass Spectrom, 25, 1184-.
43
Choi, M. H.. (2014). . J. Invest. Dermatol, 20, 1626-.
44
Ross, R. K.. (1992). . Lancet, 339, 887-.
45
Pettaway, C. A.. (1999). . J. Natl. Med. Assoc, 91, 653-.
46
Hoffman, R.. (2000). . Eur. J. Dermatol, 10, 410-.
47
Eliassen, A. H.. (2008). . Cancer Epidemiol. Biomarkers Prev, 17, 2029-.
48
Arslan, A. A.. (2009). . Cancer Epidemiol. Biomarkers Prev, 18, 2273-.
49
Liehr, J. G.. (1996). (3294-). Proc. Natl. Acad. Sci. USA.
50
Castagnetta, L. A. M.. (2002). . Clin. Cancer Res, 8, 3146-.
51
Moon, J. Y.. (2013). . BMC Clin. Pathol, 13, 25-.
52
Choi, M. H.. (2011). . J. BMC Cancer, 11, 342-.
- 투고일Submission Date
- 2014-05-27
- 수정일Revised Date
- 2014-06-05
- 게재확정일Accepted Date
- 2014-06-05
권호 내 다른 논문
- Diagnostic Evaluation of Enzyme Activity Related to Steroid Metabolism by Mass Spectrometry-Based Steroid Profiling
- Simultaneous Determination of Five Porphyrins in Human Urine and Plasma Using High Performance Liquid Chromatography-Tandem Mass Spectrometry
- Tertiary Matrices for the Analysis of Polyethylene Glycols Using MALDI-TOF MS
- Optimization of Enzyme Digestion Conditions for Quantification of Glycated Hemoglobin Using Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry
- Accurate Measurement of Arsenic in Laver by Gravimetric Standard Addition Method Combined with High Resolution Inductively Coupled Plasma Mass Spectrometry
- more
추천 논문
학술지 홈페이지 이용 환경은 크롬 브라우저 사용을 권장합니다.