- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Log In/Sign Up
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
The Clinical Effects of Ahnjeonbaekho-tang (AJBHT) on Graves’ Disease : A Prospective Clinical Study
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2005, v.26 no.4, pp.122-129
(College of Oriental Medicine, Kyung Hee University)
(College of Oriental Medicine, Kyung Hee University)
(College of Oriental Medicine, Kyung Hee University)
(College of Oriental Medicine, Kyung Hee University)
(College of Oriental Medicine, Kyung Hee University)
(College of Oriental Medicine, Kyung Hee University)
(College of Oriental Medicine, Kyung Hee University)
Soon-Il,
K.
, Ki-Hoon,
K.
, Young-Seok,
K.
, Sang-Heon,
L.
, Byung-Cheol,
L.
, Young-Min,
A.
, Ho-Kyung,
D.
, &
Se-Young,
A.
(2005). The Clinical Effects of Ahnjeonbaekho-tang (AJBHT) on Graves’ Disease : A Prospective Clinical Study. Journal of Korean Medicine, 26(4), 122-129.
- Downloaded
- Viewed
Abstract
Objectives : Graves' disease is the most common cause of hyperthyroidism, and its pathogenesis includes thyroid specific autoimmunity. Anti-thyroid drugs are widely used for regulating the thyroid function. However, in spite of long-term therapy with anti-thyroid drugs, about 40~70% of the treated patients have a relapse, and some suffer adverse effects. In this study, to evaluate the clinical efficacy of Ahnjeonbaekho-tang(AJBHT) on Graves' disease patients, we performed the clinical study prospectively. Methods : Through the thyroid function test(TFT) of 54 patients diagnosed as Graves' disease in other hospitals, 21 patients were assigned into the study. After the withdrawal of anti-thyroid drugs, AJBHT was administerd to patients for 2 months. At the same time, TFT, TSH binding inhibiting immunoglobulin(TBII) level and visual analogue scales (VAS) about fatigue and palpitation were measured before and after administration. Thirteen patients have completed the entire follow-up of this study over two months. Results : Serum levels of T3 and FT4 were significantly improved by AJBHT(T3: 298.85±79.60 ng/㎗ 181.15±33.92 ng/ ㎗ p<0.001, FT4: 2.78±1.06 ng/㎗→1.78±0.83 ng/㎗ p<0.05). However, there were no significant changes in TSH and TBII values. And the VAS scores of fatigue and palpitation also were significantly improved(5.80±3.01→3.60±2.63, p<0.05; 6.19±2.09→3.60±2.46, p<0.01). Patients' age was related to the post-treatment FT4 values(p<0.05). Conclusions : From these results, we suggest that AJBHT is effective on the TFT and the symptoms of Graves' disease, and is a safe alternative drug for Graves' disease patients.
- keywords
- Graves' disease, Ahnjeonbaekho-tang, thyroid function test, TSH binding inhibiting immunoglobulin, visual analogue scale
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- The Effects of Danchunwhangagam on LPS or DFX-induced Cytokine Production in Peripheral Mononuclear Cells of Cerebral Infarction Patients
- Armeniacae Semen Extract Induces Apoptosis in Mouse N2a Neuroblastoma Cells
- Changes of Serum VEGF and b-FGF in 26 Patients with Breast Cancer after Treatment with Hang-Am-Dan (HAD), an Antiangiogenic Botanical Prescription
- Effects of Morindae Officinalis Radix on the Spermatogenesis and Antioxidant Activities in the SD Rat
- Efficacy of Oral Korean Red-ginseng on sCRP and Soreness after Muscle Damage
- Effects of Ampelopsis Radix Extracts on Tumor Immunity
- Effect of Baekyeum on Intestinal Motility
- The Ergogenic Effects of Red Ginseng and Paeonia radix Mixtures
- The Protective Effect of Paeoniae Radix Extract against 1-methyl-4- Phenylpyridium-induced Apoptosis on SK-N-MC Neuroblastoma Cells
- Neuroprotective Effect of Ginseng radix on ICH - induced Rats
- Effect of Acupuncture on 6-Hydroxydopamine-induced Nigrostriatal Dopaminergic Neuronal Cell Death in Rats
- Amygdalin Extract from Armeniacae semen Induces Apoptosis in Human COLO 201 Colon Cancer Cells
- The Clinical Effects of Ahnjeonbaekho-tang (AJBHT) on Graves’ Disease : A Prospective Clinical Study
- Amygdalin Extract from Armeniacae Semen Induces Apoptosis through Bax-dependent Caspase-3 Activation in Human Cervical Cancer Cell Line ME-180
- Clinical Study on the Effect of Exterior Vascular Laser Irradiation Therapy by Live Blood Analysis
- Harpagophytum Procumbens Suppresses Lipopolysaccharide Induced Expressions of Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in Mouse BV2 Microglial Cells
- Interpretation of the Five Viscera’s Ascending Kidney-Water and Descending Heart-Yang
- Case study of HBV-related Disasters in a High-risk Family
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.