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E-ISSN : 2733-4538
The present study investigated the memory outcome of anterior temporal lobectomy(TL). 21 right and 17 left TL patients who passed the inclusion criteria(having confirmed hippocampal sclerosis, right-handed, older than 16 years, and full scale IQ higher than 69) performed logical memory, verbal paired associate, visual reproduction, and visual paired associate about 2 month before and 16 month after the surgery. In the MANOVA, four-way interaction among side of surgery(left/right), memory material(verbal/visual), phase(pre/post operation), and gender was significant. The source of effect was analyzed to locate in verbal memory improvement of women after left TL and that of men after right TL. It implies that material-specific memory decline in ipsilateral lobe, release of function in the contralateral lobe, and higher plasticity of verbal memory in women as a gender difference may interact to determine the pattern of memory change. In addition we explored the predicting variables of memory change. To the prediction of verbal memory change, age at operation made a significant contribution, but pre-operation memory level or age at onset did not. On the other hand, as for the visual memory we failed to find any predicting variable. To solve the null result from visual memory, a proposal to adopt the position memory task as an alternative measure was presented.
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