E-ISSN : 2733-4538
Prior studies have reported a significant correlation between negative symptoms and executive functioning in schizophrenia. We investigated whether the correlation is specific to executive functioning or reflect a more general relationship between negative symptoms and cognitive functioning. Based on PANSS Negative Scale, 36 schizophrenic patients were divided into two groups, one group with high negative symptoms (High NS group; n = 18) and the other group with low negative symptoms (Low NS group; n = 18). High NS group had a significantly low Executive IQ (EIQ) relative to Low NS group. However, the two groups did not significantly differ in Full-scale IQ (FIQ). Thus, High NS group had a selective deficit in executive functioning relative to Low NS group. These results indicate that correlation between negative symptoms and executive functioning reflects a specific relationship between the two. The specific correlation between negative symptoms and executive functioning may reflect a common pathological process, namely, frontal dysfunction.
(2000) 정신분열병 하위집단에 따른 지능 및 실행 기능 장애,
(2003) 정신분열병에서 특정 증상군에 따른 신경인지 기능의 차이,
(2002) 정신분열병 환자에서 자기공명영상 구획화를 이용한 전두엽 하위구조의 구조적 이상 관찰,
(1999) Rey-Kim 기억검사: 해설서, 대구: 도서출판 신경심리
(2001) Kims 전두엽-관리기능 신경심리검사: 해설서, 대구: 도서출판 신경심리.
(2003) 지능검사와 신경심리검사는 무엇이 다른가,
(2006) Wechsler 지능검사에서 관리기능과 비관리기능의 비교,
(1996) 정신분열병 환자의 양성 및 음성 증상과 관련된 인지적 손상의 특성,
(2004a) 정신분열병 환자의 전두엽-관리기능,
(2004b) 정신분열병 환자의 지능,
(1992) . K-WAIS 실시요강. 서울,
(2005) 정신분열증의 음성증상과 전두엽-관리기능의 관계,
(1991) . 양성 및 음성 증후군척도 평가지침서. 서울,
(2000) Cognitive functioning and negative symptoms in schizophrenia. In T. Sharma & P. Harvey (Eds.), Cognition in schizophrenia: impairments, importance and treatment strategies , New York: Oxford University Press.
(1994) . Diagnostic and statistical manual of mental disorders. 4th ed. Washington DC,
(1982) . Negative symptoms in schizophrenia definition and reliability. Archives of General Psychiatry,
(1999) Volumetric analysis of frontal lobe regions in schizophrenia: relation to cognitive function and symptomatology,
(1998) Neuropsychological correlates of negative, disorganized and psychotic symptoms in schizophrenia.,
(1968) . Differential behavioral effects in frontal lobe disease. Neuropsychologia,
(1997) Differential relationships between positive and negative symptoms and neuropsychological deficits in schizophrenia,
(1995) Schizophrenia-a brain disease?: a critical review of structural and functional cerebral abnormality in the disorder,
(1980) . Molecular pathology of schizophrenia,
(1995) Cognitive disorders in the positive, negative, and disorganization syndromes of schizophrenia.,
(2002) Correlation between clinical syndromes and neuropsychological tasks in unmedicated patients with recent onset schizophrenia,
(1993) . The frontal lobes. In K. M. Heilman & E. Valenstein, Oxford University Press.
(2003) Can specific deficits in executive functioning explain the negative symptoms of schizophrenia,
(1997) Assessment of the dysexecutive syndrome in schizophrenia,
(2006) Negative symptoms and cognitive deficits: what is the nature of their relationship?,
(1998) Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. ,
(1987) . Schizophrenic syndromes,
(1999) INS Dictionary of Neuropsychology, New York: Oxford University Press.
(1998) Executive-frontal lobe cognitive dysfunction in schizophrenia: a symptom subtype analysis,
(1990181-192.) . Neurological signs and the positive-negative dimension in schizophrenia. Biological Psychiatry,
(2001) Neuropsychological correlates of schizophrenic syndromes in patients treated with atypical neuroleptics.,
(2000) Cognitive correlates of the negative, disorganized, and psychotic symptom dimensions of schizophrenia.,
(2000) Executive dysfunction in schizophrenia. In T. Sharma & P. Harvey (Eds.), Cognition in schizophrenia: impairments, importance and treatment strategies , New York: Oxford University Press.
(1987) a normative study with adults. Developmental Neuropsychology,
(1994) . Relationship of prefrontal and temporal lobe MRI measures to neuropsychological performance in chronic schizophrenia. Biological Psychiatry,
(1935) . Studies of interference in serial verbal reactions. Journal of Experimental Psychology,
(2002) Frontal systems behavior scale in schizophrenia: relationships with psychiatric symptomatology, cognition, and adaptive function,
(1986) . Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia I. Regional cerebral blood flow evidence. Archives of General Psychiatry,
(1999) Schizophrenia and the frontal brain: a quantitative review,