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E-ISSN : 2733-4538
In an attempt to compare the brain activity between patients with major depressive disorder (MDD) and a normal control group, we analyzed the Quantitive Electroencephalography (QEEG) and we evaluated the possibility of QEEG as a useful clinical tool. The taditional measures of absolute and relative power and frequency, and the asymmetry measures were derived from the ranges of the delta, theta, alpha and beta frequencies. The asymmetry indexes were computed using two different formulas: the PCT index and the A index. The results showed the following. (1) The delta relative to power was increased and the alpha relative to power was decreased in the depressed patients, as compared to the controls. (2) The delta frequency was slower and the alpha frequency was faster in the depressed patients, as compared to the controls. (3) With the A index, the alpha and beta asymmetries were indicative of the left frontal and central hypoactivity, respectively, as was previously reported for MDD patients. However, theta asymmetry was also found in the PCT index, in addition to the alpha and beta asymmetries. Discriminant analysis correctly classified 82.6% and 87% of the patients (Ed note: check this.) when the A index and the PCT index were included, respectively. It was found that spectrally analyzed EEG could become a useful tool when diagnosing major depression and also for examining the basis of the symptoms.
강연욱 ; 이병철 ; 오은아 ; 김진혁 ; 유경호, (2006) 혈관성 치매 집단에서의 우울증과 인지기능 및 병소의 관계, 한국심리학회지 임상
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