E-ISSN : 2733-4538
The present study examined visual deficits in patients with Alzheimer's disease (AD), with a special focus on the perception of movement. Eighteen patients with mild AD viewed displays containing eight volumetric objects. Equal numbers of younger and older adults served as the controls. Each object rendered in a random check texture-mapped image appeared on the monitor and underwent rotation against a background rendered in the same texture-mapped image. Texture density also varied as part of control. Wooden objects constructed in the same proportion were used as response stimuli. In the visual task, participants identified the matching wooden object as the one depicted graphically by pointing to it. In the tactile task, they identified the matching object after probing each response stimulus using only one hand. Because the displays were lateralized such that each stimulus object was presented in either the left or right visual field, the tactile task served to examine the interhemispheric interaction. The results of the visual task showed that patients with AD performed poorly in comparison to individuals in other groups. By contrast, the older adults and patients with AD both performed poorly on the tactile task, with the performance of the AD group deteriorating even further. The finding of poor performance on the visual task is consistent with the findings of similar studies demonstrating that AD affects several aspects of vision. The present results extended these results further to suggest that movement perception is impaired in AD. The equally poor performance on the tactile task investigating the intra and interhemispheric conditions indicates that there is no disproportionate impairment of cortical connectivity in AD, at least in the domain of visual processing. The results of this study demonstrate the need for a more comprehensive diagnostic measure of AD that encompasses a broader spectrum of visual functions than that examined by the measure currently available.
강연욱, (2006) K-MMSE(Korean-Mini Mental State Examination)의 노인 규준 연구, 한국심리학회지:일반
강수진, (2001) 알쯔하이머 환자가 처음으로 병원을 찾는 시기, 대한신경학회지
현명호 ; 곽경현 ; 유정헌, (2006) 교육수준에 따른 알츠하이머형 치매 환자의인지 부호화 사용의 차이: 언어적, 시공간적,동작적 부호화를 중심으로, 한국심리학회지 임상
김정수, (2008) 급증하는 ‘실버 운전’ 안전대책 빨간불, 중앙SUNDAY
나덕렬, (1997) 치매의 신경학과 신경심리학적특성, 한국임상심리학회 월례 학술발표회 자료집.
대한치매학회, (2006) 치매:임상적 접근, 서울: 아카데미아
강연욱 ; 박재설 ; 진주희 ; 나덕렬, (2005) 알쯔하이머형 치매와 혈관성 치매의 시공간구성능력의 비교: Rey Complex Figure Test의 반응을 중심으로, 한국심리학회지 임상
박태균, (2008) 치매, 약으로 다스린다구요?, 중앙일보
보건복지부, (2007) 치매노인에 대한 대책 시급,‘07년 40만명 추정, 보건복지부 보도자료.
류경희 ; 강연욱 ; 오경자 ; 한승경 ; 이재홍, (2006) 신경심리평가 수행을 통한 초기 알쯔하이머형 치매와 혈관성 치매의 신경심리학적 변별, 한국심리학회지 임상
Ball,K.K., (1998) Age and visual search: expanding the useful field of view, Journal of the Optical Society of America A
Binder,L.M., (1982) Constructional strategies on complex figure drawing after unilateral brain damage, Journal of Clinical Neuropsychology
Binetti,G., (1998) Visual and spatial perception in the early phase of Alzheimer's disease, Neuropsychology
Cronin-Golomb,A., (1995) Vision in Alzheimer's disease, Gerontologist
Cronin-Golomb,A., (1995) Visual dysfunction predicts cognitive deficits in Alzheimer's disease, Optometry and Vision Science
Cronin-Golomb,A., (1991) Visual dysfunction in Alzheimer's disease: Relation to normal aging, Annals of Neurology
Delbeuck,X., (2003) Alzheimer’s disease as a disconnection syndrome?, Neuropsychology Review
(2004) Department of Highway Safety & Motor Vehicles ,The effects of aging on driving ability. Florida,
Dunne,T, (2004) Improved performance on activities of daily living in Alzheimer's disease: Practical applications of vision research. Vision in Alzheimer's disease., Basel: Karger.
Festa,E.K., (2005) Neocortical disconnectivity disrupts sensory integration in Alzheimer’s disease, Neuropsychology
Gilmore,G.C., (2005) Enhanced stimulus contrast normalizes visual processing of rapidly presented letters in Alzheimer's disease, Vision Research
Gilmore,G.C., (1995) Contrast sensitivity in Alzheimer's disease: A one-year longitudinal analysis, Optometry and Vision Science
Goldstein,E.B, (2007) Sensation and Perception (7th Ed.), Belmont, CA: Wadsworth.
Haegerstrom-Portnoy,G., (1999) Seeing into old age: Vision function beyond acuity, Optometry and Vision Science
Kurylo D.D., (1994) Broad-band visual capacities are not selectively impaired in Alzheimer's disease, Neurobiology of Aging
Lakmache,Y., (1998) Interhemispheric disconnection syndrome in Alzheimer's disease, Proceedings of the National Academy of Sciences of the United States of America
Levine,D.N., (1993) The visual variant of Alzheimer’s disease, A clinico-pathologic case study, Neurology
Lezak,M.D, (1995) Neuropsychological assessment(2nd Ed.), Oxford.
Mckhann,G., (1984) Clinical diagnosis of Alzheimer's disease, Neurology
Mendez,M.F., (1990) Complex visual disturbances in Alzheimer's disease, Neurology
Mendola,J.D., (1995) Prevalence of visual deficits in Alzheimer's disease, Optometry and Vision Science
Mesulam,M.M, (1998) From sensation to cognition, Brain
Morris,R.G., (1996) Neurobiological correlates of cognitive dysfunction. The cognitive neuropsychology of Alzheimertype dementia., Oxford, UK: Oxford University Press.
Neary,D., (1987) Perceptuospatial disorder in Alzheimer's disease, Seminars in Ophthalmology
Nguyen,A.S., (2003) Visual identification and spatial location in Alzheimer's disease, Brain and Cognition
Norman,J.F., (2006) Aging and the perception of 3-D shape from dynamic patterns of binocular disparity, Perception & Psychophysics
Norman,J.F., (2006) Aging and the visual,haptic,and cross-modal perception of natural object shape, Perception
Owens,D.A, (1999) Effects of luminance, blur, and age on nighttime visual guidance: A test of the selective degradation hypothesis, Journal of Experimental Psychology: Applied
Peters,A, (1996) Neurobiological bases of age-related cognitive decline in the rhesus monkey, Journal of Neuropathology and Experimental Neurology
Reuter-Lorenz,P.A., (2005) split-brain model of Alzheimer's disease? Behavioral evidence for comparable intra and interhemispheric decline, Neuropsychologia
Rizzo,M., (2000) Vision and cognition in Alzheimer's disease, Neuropsychologia
Rizzo,M., (1998) Perception of movement and shape in Alzheimer's disease, Brain
Sathian,K, (1995) Motion perception in Alzheimer's disease, Neurology
Schiffer,F, (1997) Affect changes observed with right versus left lateral visual field stimulation in psychotherapy patients: possible physiological, psychological, and therapeutic implications, Comprehensive Psychiatry
Silverman,S.E., (1994) Dissociation between the detection and perception of motion in Alzheimer's disease, Neurology
Sperry,R.W, (1961) Cerebral organization and behavior, Science
Stevens,J.C, (1992) Aging and the spatial acuity of touch, Journal of Gerontology: Psychological Sciences
Uc,E.Y., (2006) Unsafe rear-end collision avoidance in Alzheimer's disease, Journal of the Neurological Sciences
Zaidel,E, (1975) A technique for presenting lateralized visual input with prolonged exposure, Vision Research