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The chemical composition and biological activities of volatile flavor components of Elsholtzia splendens
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2005, v.18 no.6, pp.500-510
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(2005). The chemical composition and biological activities of volatile flavor components of Elsholtzia splendens. Analytical Science and Technology, 18(6), 500-510.
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Abstract
향료자원 꽃향유 전초의 향기성분 essential oil, absolute 및 oleoresin을 추출 분리 동정하고,지질과산화 억제, 세포독성, 돌연변이유발성 및 거담효과 등의 생리활성을 측정하였다. 꽃향유 전초의essential oil 수율은 0.28%이었으며, 2-cyclohexen-1-one이 26.81%와 elsholtizia ketone이 13.46%로 가 장 많이 함유되어 있었다. 꽃향유 전초의 absolute의 수율은 12.45%이었으며, methyl linolenate가12.38%이었고, palmitic acid 9.47% 비율로 존재하고 있었다. 꽃향유 전초의 oleoresin의 수율은 9.95%이었으며, 9,12,15-octadecatrienoic acid가 22.15%로 가장 높은 비율을 차지하고 있었다. 세 방법의 지질과산화 억제활성 시험에서 200 μg/ml 처리했을 때 꽃향유전초의 essential oil과 oleoresin은 지질과산화를 잘 억제하였으나, absolute는 거의 억제하지 못하였다. 꽃향유 전초의 oleoresin은 24시간에서EC50값이 17.6 μg/ml로 고농도에서만 약간의 세포독성이 있으며, absolue와 oleoresin은 고 농도에서도돌연변이 유발성과 항균성이 나타나지 않았으나 essential oil은 500 μg이상 처리 시 돌연변이 유발성뿐만 아니라 항균성도 있는 것으로 나타났다. 꽃향유 전초의 essential oil과 oleoresin은 약간의 거담 효과는 있을 것으로 판단된다.
- keywords
- Elsholtzia splendens, volatile flavor components, NRU assay, Ames test, ciliostasis, lipid peroxidation
Reference
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(2004) Kor. J. Med. Crop. Sci.,
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