- P-ISSN 1225-0163
- E-ISSN 2288-8985
To help understanding about hazard chemicals occurring newly in food, it has been reviewed characteristics, mechanism, food standards and analytical trend of the hazard chemicals occurring avoidably in food manufacturing process. The new hazard chemicals in food are classified by 4 regarding mechanism such as heat, fermentation, additives and unknowns. The new hazard chemicals by heat process are acrylamide, furan, HCAs and PAHs. By the fermentation, ethylcarbamate and biogenic amines are occurred. According to food additives, 3-MCPD, benzene and nitrosamines can be produced. And the last group is the illegal compounds including anti-impotence drug analogues and anti-obesity drug analogues. To analyze the new hazard chemicals in food, GC or LC with UVD, FLD or MSD are used mainly after sample pretreatment by LLE, SPE or headspace method.
1. O. R. Fennema, ‘Food Chemistry’, 2nd Ed., Marcel Dekker Inc., New York, USA, 1985.
2. P. Linko, ‘Food Process Engineering’, Vol. 1, Applied Science Publishers Ltd.,1980.
3. 채수규, ‘표준식품화학’, 효일(ISBN 8985768832), 2000.
4. 식품의약품안전청, ‘식품공전’, 2008.
5. 식품의약품안전청, ‘식품첨가물공전’, 2007.
6. D. Sharp, Lancet, 361, 361-362(2003).
7. E. Tareke, P. Rydberg, P. Kaylsson, S. Eriksson and M. Tornqvist, J. Agric. Food Chem., 50, 4998-5006(2002).
8. A. Adams, K. A. Tehrani, M. Kersiene, R. Venskutonis and N. Kimpe, J. Agric. Food Chem., 51, 4338- 4343 (2003).
9. US FDA (http://fda.gov).
10. K. Skog, M. Johansson and M. Jagerstad, Food. Chem. Toxicol., 36, 879-896(1998).
11. M. Murkovic, J. Chromatogr. B, 802, 3-10(2004).
12. S. Moret and L. Conte, J. Chromatogr. A, 882, 245- 253(2000).
13. A. Pupin and M. Toledo, Food Chem., 55, 185-188 (1996).
14. T. Wenzl, R. Simon, J. Kleiner and E. Anklam, Trends in Anal. Chem., 25, 716-725(2006).
15. C. Ough, J. Agric. Food Chem., 24, 323-328(1976).
16. R. Battaglia, H. Conacher and B. Page, Food Addit. Contam., 4, 477-496(1986).
17. FDA Report, Scombrotoxic(Histamine) Formation, Chpter 7(2001).
18. e-Letter of New Hazard Chemicals (http://blog.korea.kr/ nhct), 2, 7-13(2007).
19. C. Maltoni and C. Scarnato, Med. Lavoro, 70, 352- 357(1979).
20. B. Halliwell and J. Gutteridge, Mol. Aspects Med., 8, 89-193(1985).
21. J. Valis, K. David, V. Kubelka, Z. Janic, Z. Svobodova and Z. Simikova, J. Agric. Food Chem., 28, 1142- 1144(1980).
22. P. Collier, D. Cromie and A. Davies, Am. Oil Chem. Soc., 68, 785-790(1991).
23. S. Yurchenko et al., Volatile N-Nitrosamines in various fish products, Food Chemistry , 96, 325-333(2006).
24. W. Lijinsky, Mutation research, 443, 129-138(1999).
25. 최동미, 임무혁, 이경진, 권광일, 정지윤, 박건상, 홍무기, 이철원, 분석과학, 17, 520-526(2004).
26. e-Letter of New Hazard Chemicals (http://blog.korea.kr/nhct), 10, 81-89(2007).
27. X. Zhu, S. Xiao, B. Chen, F. Zhang, S. Yao, Z. Wan, D.Yang and H. Han, J. Chromatogr. A, 1066, 89-95(2005).
28. D. Zhong, J. Xing, S. Zhang and L. Sun, Rapid Commun. Mass Spectrom., 16, 1836-1843(2002).
29. 정형욱, 박성국, 최동미, 분석과학, 20, 164-169(2007).
30. T. Wenzl L. Karas, J. Rosen, K.-E. Hellenaes, C. Crews, L. Castle and E. Anklam, J. Chromatogr. A, 1132, 211- 218(2006).
31. C. Kim, E. Hwang and H. Lee, Food Chem., 101, 401- 409(2007).
32. M. Lee, L. Chang and J. Dou, Anal. Chim. Acta, 582, 19-23(2007).
33. 허수정, 우건조, 최동미, 분석과학, 20, 170-175(2007).
34. S. Tfouni, R. Machado, M. Camargo, S. Vitorino, E. Vicente and M. Toledo, Food Chem., 101, 334- 338(2007).
35. G. Diletti, G. Scortichini, R. Scarpone, G. Gatti, L. Torreti and G. Migliorati, J. Chromatogr. A, 1062, 247- 254(2005).
36. A. Barranco, R. Alonso-Salces, A. Bakkali, L. Berrueta, B. Gallo, F. Vicente and M. Sarobe, J. Chromatogr. A, 988, 33-40(2003).
37. US EPA Method 1624(1989).
38. 김은주, 박상애, 최동미, 식품위생안전성, 22, 243- 247(2007).
39. 식품의약품안전청 연구보고서, 8, 643(2006).
40. 박성국, 윤태형, 최동미, 분석과학, 21, 53-57(2008).
41. D. Lachenmeier, W. Frank and T. Kuballa, Rapid Commum. Mass Spectrom., 19, 108(2005).
42. R. Dyer, J. AOAC Int., 77, 64-66(1994).
43. D. Choi, S. Park, T. Yoon, H. Jeong, J. Pyo, J. Park, D. Kim and S. Kwon, J. AOAC Int., 91, 580-588(2008).
44. 최동미, 분석과학, 21, 65-83(2008).
45. M. Nout, M. Rulikes, H. Bouwmeester and P. Beljaars, J. Food Safety, 13, 293-303(1993).
46. E. J. Mitacek et al., Food and Chemical Toxicology, 37, 297-305(1999).
47. 식품의약품안전청 연구보고서, 9, 115-116(2005).
48. A. Shalaby, Food Research Int., 29, 675-690(1996).
49. 식품의약품안전청 신종유해물질과, ‘식품 중 신종물질 분석방법 총서’, (행정간행물등록번호; 11- 1470000-001653-10), 2008.
50. 식품의약품안전청, ‘식품 중 3-MCPD, 바이오제닉아민, HCAs 저감화실행규범’, (행정간행물등록번호; 11-1470000-001742-14), 2008.
51. 식품의약품안전청, ‘신종유해물질 Q&A’, (행정간행물등록번호; 11-1470000-001690-14), 2008.
52. 식품의약품안전청 홈페이지 (http://www.kfda.go.kr).
53. IARC Monographs (http://monographs.iarc.fr)
54. JECFA Homepage (http://codexalimentarius.net/web/jecfa. jsp)
55. 식품의약품안전청고시 제2007-10호 (http://www.kfda.go.kr).
56. 식품의약품안전청 연구보고서, 9, 903-904(2005).
57. 식품의약품안전청고시 제2008-52호 (http://www.kfda.go.kr).