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- E-ISSN 2288-8985
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Application of Negative Ion Mass Spectrometry in Amino Acid Analysis
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1993, v.6 no.1, pp.77-82
Pyo,
D.
(1993). Application of Negative Ion Mass Spectrometry in Amino Acid Analysis. Analytical Science and Technology, 6(1), 77-82.
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Abstract
Negative chemical ionization mass spectrometry(NCI-MS) can provide the enhancement in sensitivity in the analysis of amino acids. For molecules which are strongly electron-capturing, NCI-MS has been of amino to have detection limits in the femtomole to attomole(<TEX>$10^{18}$</TEX>) range. Because of the selectivity of the ionization process, background noise is diminished, further enhancing signal to noise ratio. In this paper, we explored a dinitro-phenyl derivatives of amino acids by NCI-MS and compared it with eletron ionization method. The results demonstrated NCI-MS produces very clean spectra with a very little noise.
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- Negative Ion Chemical Ionization, Amino Acid Analysis
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