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Efficacy of two commonly used potentized homeopathic drugs, Calcarea carbonica and Lycopodium clavatum, used for treating polycystic ovarian syndrome (PCOS) patients: II. Modulating effects on certain associated hormonal levels

CELLMED / CELLMED, (P)3022-6805; (E)3022-6791
2016, v.6 no.1, pp.7-7
Debarsi Das (Mahesh Bhattacharyya Homeopathic Medical College and Hospital)
Indira Das (Gangadharpur Sikshan Mandir)
Jayeeta Das (University of Kalyani)
Saroj Kumar Koyal (Mahesh Bhattacharyya Homeopathic Medical College and Hospital)
Anisur Rahman Khuda-Bukhsh (University of Kalyani)

Abstract

In view of greater attention given to the incidence of Polycystic Ovarian Syndrome (PCOS) in women of reproductive age, particularly in urban and semi-urban population in India, research works in both the regimens of orthodox and complementary and alternative medicines have been rejuvenated in recent years. We report here relative efficacy of two potentized homeopathic remedies, Calcarea carbonica (Calc) and Lycopodium clavatum (Lyco) used traditionally for the removal of ovarian cysts. These drugs are most frequently used based on guiding symptoms of individual patients. Effects of either of these remedies on its ability of removing cysts, along with amelioration of certain other hormones and hormone-related parameters of PCOS, such as follicle stimulating hormone, luteinizing hormone, Estradiol, Testosterone (Free/Total), Dehydroepiandosterone, Prolactine, Progesterone (17- Hydroxyprogesterone), TSH including T3, T4, and Insulin were studied. The Insulin-related parameters like changes in fasting or post-prandial glucose levels were also studied. The mentioned hormones play some- direct or indirect roles in causing irregular menstrual cycle and PCOS. The data collected at three fixation time points, namely, at 6, 12, and 18 months were considered. Results showed that out of 40 patients initially having PCOS, cysts were totally removed in 21 patients along with amelioration of other relevant symptoms. Both Calc and Lyco had amelioration of similar nature. Results of this study therefore validate safe and effective use of both Calc and Lyco in homeopathy, to patients with basic guiding symptoms for either drug, and can be recommended for patients with PCOS as they do not have any reported side-effects.

keywords
polycystic ovarian syndrome, homeopathy, Calcarea carbonica, Lycopodium clavatum, hormones

Reference

1.

Allen HC. Keynotes and characteristics with comparisons of some of the leading remedies of the materia medica with nosodes. 2nd ed. (New Delhi, India; B Jain Publishers Pvt. Ltd.), 2002.

2.

Banaszewska B, Spaczyński RZ, Pelesz M, Pawelczyk L. Incidence of elevated LH/FSH ratio in polycystic ovary syndrome women with normo- and hyperinsulinemia. Rocz Akad Med Bialymst. 2003;48:131-134.

3.

Boericke W. Pocket Manual of Homoeopathic Materia Medica & Repertory: Comprising of the Characteristic and Guiding Symptoms of All Remedies (clinical and Pahtogenetic [sic])Including Indian Drugs. 2nd ed. (New Delhi, India: B. Jain Publishers (P) Ltd), 2002.

4.

CCRH. Homoeopathy in polycystic ovarian syndrome: A randomized placebo-controlled pilot study. Indian J Res Homoeopathy. 2014;8:3-8.

5.

Close S. The Genius of Homoeopathy: Lectures and Essays on Homoeopathic Philosophy. 2nd ed. (New Delhi, India: Indian Books & Periodicals Publishers), 2003.

6.

Das D, Das I, Das J, Kayal SK, Khuda-Bukhsh AR. Efficacy of two traditionally used potentized homeopathic medicines, Calcarea carbonica and Lycopodium clavatum, used for treating PCOS patients: I. Effects on certain important external guiding symptoms. TANG. 2016. [In press]

7.

Dasgupta S, Dutta J, Annamaneni S, Kudugunti N, Battini MR. Association of vitamin D receptor gene polymorphisms with polycystic ovary syndrome among Indian women. Indian J Med Res. 2015;142:276-285.

8.

Gill H, Tiwari P, Dabadghao P. Prevalence of polycystic ovary syndrome in young women from North India: A Communitybased study. Indian J Endocrinol Metab. 2012;16:S389-S392.

9.

Hahnemann S, Künzli J. Organon of Medicine. 6th ed. (Traverse City, USA; Cooper Publishing), 1982.

10.

Homoeopathic Pharmacopoeia Committee, Ministry of Health, Ministry of Health and Family Welfare. Homoeopathic Pharmacopoeia of India (H.P.I.). (Delhi, India; Controller of Publications), 1971.

11.

Kent JT. Lectures on Homeopathic Materia Medica: Together with Kent's "new Remedies" Incorporated and Arranged in One Alphabetical Order. 2nd ed. (Noida, India; B Jain Publishers Pvt. Ltd.), 1985.

12.

Lin MW, Wu MH. The role of vitamin D in polycystic ovary syndrome. Indian J Med Res. 2015;142:238-240.

13.

Rashidi B, Haghollahi F, Shariat M, Zayerii F. The effects ofcalcium-vitamin D and metformin on polycystic ovary syndrome: a pilot study. Taiwan J Obstet Gynecol. 2009;48:142-147.

14.

Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long‐term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19:41-47.

15.

Van Weemen BK1, Schuurs AH. Immunoassay using antigenenzyme conjugates. FEBS Lett. 1971;15:232-236.

16.

Woodhead JS, Weeks I. Chemiluminescence immunoassay. Pure Appl Chem. 1985;57:523-529.

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