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E-ISSN : 2733-4538
The implicit memory deficit in patients with obsessive-compulsive disorder (OCD) was investigated using event-related potentials. For the measurement of implicit memory, a lexical decision task was administered. Among 320 words and 140 non-words, 200 words were repeated, 120 words and 140 non-words were not repeated. For explicit memory a continuous recognition task was administered, in which 280 words were repeated (old) and 100 were not repeated (new). On the recognition task, both controls and OCD patients showed more positivity to the old words than the new words (repetition effect). The two groups did not differ in terms of the performances on Korean version of California verbal learning test, but OCD patients showed impaired performances on immediate and delayed recalls of Rey-Osterrieth complex figure test (RCFT). On the lexical decision task, controls showed the repetition effect, whereas OCD patients did not. In addition, OCD patients showed prolonged response time to the old words compared to the controls. The results of source localization, which was performed to find the cerebral generators of repetition effect, showed that left caudate body is a strong candidate for the generator. The absence of the repetition effect on the implicit memory task and the impaired performance on RCFT indicate that OCD patients have implicit memory deficit, which seems to be caused by encoding or organizational difficulties. Furthermore, implicit memory deficit in OCD patients seems to be related to the dysfunction of prefrontal-striatal system, which is known as the neural substrates underlying OCD.
(1999) K-CVLT 신경심리학적 기억검사 실시요강, 도서출판
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