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Depression and Baseline Prefrontal EEG Alpha Wave Asymmetry

Abstract

The aim of this study was to examine the relationship between alpha asymmetry in prefrontal cortex (PFC) electroencephalography (EEG) and depression. We compared the resting baseline PFC alpha activity of a depressed patient group (N = 59) and that of a healthy control group (N = 29). Using one way ANOVAs, significant group effects were found in all asymmetry indexes. The depression group showed relatively low activity in the left PFC. There were no significant effects of episode state or diagnostic subtype. There were no differences in asymmetry indexes between current depressed patients and previously depressed patients. We could not find any differences in asymmetry scores between the major depressive disorder group and the other depression group. These results indicate that PFC EEG asymmetry is a trait marker for depression.

keywords
전두엽 비대칭, 정량적 뇌전위, 우울증, 전전두엽, 기분장애, electroencephalography, EEG, frontal asymmetry, depression, prefrontal cortex, affective disorder, electroencephalography, EEG, frontal asymmetry, depression, prefrontal cortex, affective disorder

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