
- P-ISSN 1225-0163
- E-ISSN 2288-8985
Analytical method of haloperidol (HAL) in serum which has been widely used in therapy of schizophrenic disorders is developed. Gas chromatography/nitrogen-phosphorus detection (GC/NPD) was used for this study. Bromoperidol was used as an internal standard and diethylether as a solvent of three-step extraction. The extraction yield in this procedure was <TEX>$67.5{\pm}1.9%$</TEX> at 15 ng/mL. A good linear response in the range of 1~40 ng/mL was obtained with correlation coefficient of <TEX>$r^2