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- E-ISSN 2288-8985
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Deermination of phenobarbital in Intact Phenobabital Tablets using NIRS
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2002, v.15 no.2, pp.102-107
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(2002). Deermination of phenobarbital in Intact Phenobabital Tablets using NIRS. Analytical Science and Technology, 15(2), 102-107.
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Abstract
This paper describes a rapid determination of phenobarbital in intact phenobarbital tablets using partial least squares regression(PLSR) method of transmittance spectrum of near infrared (NIR) compared with the analytical data of liquid chromatograpy. The linearity, concentration range and precision of this analytical method are studied. The correlation coefficient of the calibration curve is 0.9983 and the standard error of calibration(SEC) is 0.14 %. Intra-day precision and Inter-day precision obtained in this method are CV
- keywords
- near infrared spectroscopy, partial least square regression, phenobarbital
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