- P-ISSN 1225-0163
- E-ISSN 2288-8985
- Log In/Sign Up
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
Article Detail
Home > Article Detail
Validation of ICP-MS method for trace level analysis of Pb in plasma
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2015, v.28 no.5, pp.309-316
https://doi.org/10.5806/AST.2015.28.5.309
&
(2015). Validation of ICP-MS method for trace level analysis of Pb in plasma. Analytical Science and Technology, 28(5), 309-316, https://doi.org/10.5806/AST.2015.28.5.309
- Downloaded
- Viewed
Abstract
The analytical method of lead in plasma by ICP-MS was validated after securing environment within class 1,000 classification. We tested specificity and accuracy of within-run and between-run. According to measurement of the amount of suspended particulates in a clean room, 0.3~62 particles were detected in 0.3 μm size while 0.0~28.3 particles were observed in 0.5 μm size. Total suspended particulates met required environment with up to 90.3 particles. The MDL (Method detection limit) of the sample which has been fabricated using fetal bovine serum (FBS) blank was 1.77 ng/L, and LOQ (Limit of quantification) was 5.55 ng/L. The slope, intercept and correlation coefficient of the calibration curve were y=1.09×10−3x+4.88×10−2 and r=0.9999, which showed good correlation. The specificity, withinrun and between-run accuracy satisfied the standard at more than 50 ng/L. The average lead concentration in plasma of the general people, current workers and retired workers was 55.4 ng/L, 440 ng/L, and 132 ng/L.
- keywords
- validation, lead, plasma, inductively coupled plasma-mass spectrometry
Reference
1
1. B. K. Lee, J. J. Kim, K. H. Woo and H. S. Kim, Health Care Technology Research and Development Annual Report, Ministry of Health and Human Services, 2002.
2
2. H. Hu, M. Rabinowitz and D. Smith, Environ. Health Perspect., 106(1), 1-8 (1998).
3
3. R. Cornelis, B. Heinzow, R. F. M. Herber, J. Molin Christensen, O. M. Paulsen, E. Sabbioni, D. M. Templeton, Y. Thomassen, M. Vahter, and O. Vesterberg, Pure & Appl. Chem., 67 (Nos 8/9), 1575-1608 (1995).
4
4. J.-W. Choi, N.-S. Kim, K.-S. Cho, J.-O Ham and B.-K. Lee, J. Korea Soc. Occup. Environ. Hyg., 20(1), 10-18 (2010).
5
5. Korea Occupational Safety & Health Agency (KOSHA), Industrial Accident Statistics, http://eip.kosha.or.kr/jsp/Main.jsp?On=OPEN, Assessed 29 Oct 2014.
6
6. M. M. Telléz-Rojo, M. Hernández-Avila,H. Lamadridfigueroa, D. Smith, L. Hernández-Cadena, A. Mercado, A. Aro, J. Schwartz and H. Hu, American J. Epidemiology, 160, 668-678 (2004).
7
7. F. Barbosa Jr., I. Ramires, M. H. C. Rodrigues, T. D. Saint’ Pierre, A. J. Curtius, M. R. Buzalaf, R. F. Gerlach and J. E. Tanus-Santos, Environ. Res., 102, 90-95 (2006).
8
8. M. Hernández-Avila, D. Smith, F. Meneses, R et al., Environ. Health Perspect., 106(8), 473-477 (1998).
9
9. F. J. Roberts, L. Ebdon and S. J. Hill, J. Trace Elements Med. Biol. 14, 108-115 (2000).
10
10. S. S. Choi, and S. H. Lee, J. Korean Soc. Environ. Adm., 8(4), 331-337 (2002).
11
11. G. R. C. Almeida, C. F. Freitas Tavares, A. M. Souza, T. S. Sousa, C. A. R. Funayama, F. Barbosa Jr., J. E. Tanus-Santos and R. F. Gerlach, Sci. Total Environ., 408, 1551-1556 (2010).
12
12. G. A. K. Koyashiki, M. M. B. Paoliello, T. Matsuo, M. M. B. Oliveira, L. Mezzaroba, M. Fátima Carvalho, A. M. Sakuma, C. Turini, M. T. O. Vannuchi, and C. S. D. Barbosa, Environ. Res., 110, 265-271 (2010).
13
13. S.-B. Lee, J.-S. Yang, S.-B. Choi and H.-S. Shin, Anal. Sci. Technol., 25(3), 190-196 (2012).
14
14. S.-B. Lee, J.-S. Yang, S.-B. Choi, N.-S. Kim, B.-K. Lee and H.-S. Shin, J. Korean Soc. Occup. Environ. Hyg., 23(2), 65-74 (2013).
15
15. M. F. Montenegro, F. Barbosa Jr., V. C. Sandrim, R. F. Gerlach, J. E. Tanus-Santos, Arch Toxicol., 80, 394-398 (2006).
16
16. V. B. Rezende, J. H. Amaral, R. F. Gerlach, F. barbosa Jr., and J. E. Tanus-Santos, J. Trace Elem. Med. Biol., 24, 147-151 (2010).
17
17. K. S. Park and S. T. Kim, Anal. Sci. Technol., 10(4), 240-245 (1997).
18
18. F. Barbosa Jr., J. E. Tanus-Santos, R. F. Gerhach and P. J. Parsons, Environ. Health Perspect., 113(12), 1669-1674 (2005).
19
19. Ministry of Food and Drug Safety, Guideline for the Validation of Bioanalytical Method, 2010.
20
20. I. A. Bergdahl, L. Gerhardsson, I. E. Liljelind, L Nilsson and S. Skerfving, Am. J. Ind. Med., 49, 93-101 (2006).
21
21. N.-S. Kim, J.-H. Kim, B.-K. Jang, H.-S. Kim, K.-D. Ahn and B.-K. Lee, J. Korean Soc. Occup. Environ Hyg., 17(1), 43-52 (2007).
22
22. M. F. Montenegro, F. Barbosa Jr, V. C. Sandrim, R. F. Gerlach and J. E. Tanus-Santos, Arch Toxicol., 80, 394-398 (2006).
23
23. C. D. Palmer, M. E. Lewis Jr., C. M. Geraghty, F. Barbosa Jr., and P. J. Parsons, Spectrochim. Acta B, 61, 980-990 (2006).
24
24. N.-S. Kim, K-S. Jung and B.-K. Lee, J. Korean Soc. Occup. Environ. Hyg., 21(4), 193-200 (2011).
25
25. K. S. Park and S. T. Kim, Anal. Sci. Technol., 10(4), 240-245 (1997).
26
26. D. Smith, M. Hernandez-Avila, M. M. Téllez Rojo, A. Merado and H. Hu, Environ. Health Perspect., 110(3), 263-268 (2002).
27
27. J. A. Nunes, B. L. Batista, J. L. Rodrigues, N. M. Caldas, J. A. Neto, and F. Barbosa Jr, J. Toxicol. Environ. Health A,. 73(13-14), 878-887 (2010).
28
28. G. R. Almeida, C. F. Freitas Tavares, A. M. Souza, T. S. Sousa, C. A. R. Funayma, F. Barbosa Jr, J. E. Tnus- Santos, and R. F. Gerlach, Sci. Total Environ., 408, 1551-1556 (2010).
29
29. E. Bárány, I. A. Bergdahl, L.-E. Bratteby, T. Lundh, G. Samuelson, A. Schütz, S. Skerfving and A. Oskarsson, Sci. Total Environ., 286, 129-141 (2002).
30
30. A. Schütz, I. A. Bergdahl, A. Ekhom and S. Skerfving, Occup. Environ. Med., 53, 736-740 (1996).
31
31. I. A. Bergdahl, A. Schütz, L. Gerhardsson, A. Jensen and S. Skerfving, Scand. J. Work Environ. Health, 23(5), 359-363 (1997).
32
32. I. A. Bergdahl, M. Vahter, S. A. Counter, A. Schütz, L. H. Buchanan, F. Ortega, G. Laurell and S. Skerfving, Environ. Res. Sect. A, 80, 25-33 (1999).
Other articles from this issue
- Validation of ICP-MS method for trace level analysis of Pb in plasma
- Simultaneous and quantitative determination of anion biocides in soil by liquid chromatography-tandem mass spectrometry
- Determination of homogentisic acid in human plasma by GC-MS for diagnosis of alkaptonuria
- Analysis of domain required for aggregates formation of ALS (Amyotrophic lateral sclerosis)/FTD (Frontotemporal dementia)-linked FUS in mammalian cells
- Counter anion effects in anion exchange membrane-fabricated non-aqueous vanadium redox flow battery
- Predictive analysis on explosive performance of methylnitroimidzole derivatives
- Study on 222Rn reduction rate in boiling groundwater
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.