바로가기메뉴

본문 바로가기 주메뉴 바로가기

ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
 

logo

Traditional oil palm (Elaeis guineensis jacq.) and its medicinal uses: A review

셀메드 / CELLMED, (P)3022-6805; (E)3022-6791
2014, v.4 no.3, pp.16-16
https://doi.org/10.5667/tang.2014.0004
Bamidele Victor Owoyele (University of Ilorin)
Gbenga Opeyemi Owolabi (Ladoke Akintola University)

Abstract

The oil palm ( Elaeis guineensis Jacq.) has been reported to originate along the gulf of the guinea in West Africa. The various parts of the tree have been used locally and traditionally for various medicinal purposes. Some of these uses have been proved by scientific experiments. Palm oil is extracted from the mesocarp of the fruit and is used traditionally for the treatment of headaches, pains, rheumatism, cardiovascular diseases, arterial thrombosis and an atherosclerosis due to its rich phytonutrients. The leaves are also used for the treatment of cancer, cardiovascular diseases, kidney diseases and wound healing. The sap also has been found to be rich in phytonutrients that can be used to treat various diseases. This review therefore seeks to explore many of the uses of the oil palm using the various parts of the oil palm.

keywords
anti-inflammatory, anti-cancer, cardiovascular diseases, Elaeis guineensis, medicinal uses, oil palm, rheumatism

참고문헌

1.

Abdullah Z, Hussain K, Zhari I, Rasadah MA, Mazura P, Jamaludin F, Sahdan R. Evaluation of extracts of leaf of three Ficus deltoidea varieties for antioxidant activities and secondary metabolites. Phcog Res. 2009;1:216-223.

2.

Abeywardena M, Runny I, Nizar M, Mohamed S, Head R. Polyphenol-enriched extract of oil palm fronds (Elaeis guineensis) promotes vascular relaxation via endothelium-dependent mechanisms. Asia Pac J Clin Nutr. 2002;11:S467-S472.

3.

Abulude FO, Ogunkoya MO, Ogunleye RF, Akinola AO, Adeyemi AO. Effect of palm oil in protecting stored grains from Sitophilus zeamais and Callosobruchus maculatus. J Entomol. 2007;4:393-396.

4.

Anyanji VU, Mohamed S, Zokti JA, Ado MA. Anti-inflammatory properties of oil palm leaf (Elaeis guineensis Jacq.) extract in aged rats. Int J Pharm Pharm Sci. 2013;5:134-136.

5.

Bester DJ, van Rooyen J, Du Toit EF, Esterhuyse AJ. Red palm oil protects against the consequences of oxidative stress when supplemented with dislipidaemic diets. Med Tech SA. 2006;21:3-6.

6.

Boateng J, Verghese M, Chawan CB, Shackelford L, Walker LT, Khatiwada J, Williams DS. Red palm oil suppresses the formation of azoxymethane (AOM) induced aberrant crypt foci (ACF) in fisher 344 male rats. Food Chem Toxicol. 2006;44:1667-1673.

7.

Bonanome A, Grundy SM. Effect of dietary stearic acid and plasma cholesterol and lipoprotein levels. New Eng J Med. 1988;318:1244-1248.

8.

Bauer AW, Kirby WM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966;45:493-496.

9.

Budin SB, Rajab NF, Osman K, Top AGM, Mohammed WNW, Bakar MA, Mohamed J. Effects of palm vitamin E against oxidative damage in Streptozotocin-induced diabetic rats. Malaysian J Biochem Mol Biol. 2006;13:11-17.

10.

Chong KP, Rossall S, Atong M. In vitro antimicrobial activity and fungitoxicity of syringic acid, caffeic acid and 4-hydroxybenzoic acid against Ganoderma boninense. J Agric Sci. 2009;1:15-20.

11.

Chong KH, Zuraini Z, Sasidharan S, Devi PVK, Latha LY, Ramanathan S. Antimicrobial of Elaeis guineensis leaf. Pharmacologyonline. 2008;3:379-386.

12.

Chong YH, Ng TK. Effects of palm oil on cardiovascular risk. Med J Malaysia. 1991;46:41-50.

13.

Choudhury N, Tan L, Truswell AS. Comparison of palm olein and olive oil: Effects on plasma lipids and Vitamins E in young adults. Am J Clin Nutr. 1995; 61:1043-1051.

14.

Corley RHV. Oil Palm Research. In the genus Elaeis, Corley RHV, Hardon JJ, Wood BJ ed. (Amsterdam, Netherlands: Elsevier Scientific Publisher), p. 532, 1976.

15.

Cottrell RC. Introduction: nutritional aspects of palm oil. Amer J Clin Nutr. 1991;53:989S-1009S.

16.

Das S, Lekli I, Das M, Szabo G, Varadi J. Cardioprotection with palm oil tocotrienols: Comparison of different isomers. Am J Physiol Heart Circ Physiol. 2008;294:70-78.

17.

Duke AJ. Handbook of Energy Crops. pp. 1-5, 1983. Available at: https://www.hort.purdue.edu/newcrop/duke_energy/Elaeis _guineensis.html (accessed on 01st May 2014).

18.

Ebong PE, Owu DU, Isong EU. Influence of palm oil (Elaesis guineensis) on health. Plant Food Hum Nutr. 1999;53:209-222.

19.

Edem DO. Palm oil: Biochemical, physiological, nutritional, hematological and toxicological aspects: a review. Plant Foods Hum Nutr. 2002;57:319-341.

20.

Edem DO. Vitamin A: A review. Asian J Clin Nutr. 2009;1:65-82.

21.

Edem DO, Akpanabiatu MI. Effects of palm oil-containing diets on enzyme activities of rats. Pak J Nut. 2006;5:301-305.

22.

Ekpa OD, Ebana RUB. Comparative Studies of Mmanyanga, Palm and Coconut Oils; Anti-microbial Effects of the Oils and their Metallic Soaps on Some Bacteria and Fungi. Global J Pure and Appl Sci. 1996;2:155-163.

23.

Ekwenye UN, Ijeomah CA. Antimicrobial effects of palm kernel oil and palm oil. KMITL Sci J. 2005;5;502-505.

24.

Elson CE. Tropical Oils: Nutritional and Scientific Issues. Crit Rev Food Sci Nutr. 1992;31:79-102.

25.

Engelbrecht AM, Esterhuyse AJ, Du Toit EF, Lochner A, Van Rooyen J. P38-MAPK and PKB/Akt, possible role players in red palm oil-induced protection of the isolated perfused rat heart? J Nutr Biochem. 2006;17:265-271.

26.

Esterhuyse AJ, Du Toit EF, Van Rooyen J. Dietary red palm oil supplementation protects against the consequences of global ischemia in the isolated perfused rat heart. Asia Pac J Clin Nutr. 2005;14:340-347.

27.

Goh SH, Khor HT, Gee PT. Phospholipids of palm oil (Elaeis guineensis). J Am Oil Chem Soc. 1982;59:296-299.

28.

Goh SH, Choo YM, Ong SH. Minor constituents of palm oil. J Am Oil Chem Soc. 1985;62:237-240.

29.

Gulecha V, Sivakuma T. Anticancer activity of Tephrosia purpurea and Ficus religiosa using MCF 7 cell lines. Asian Pac J Trop Med. 2011;4:526-529.

30.

Guthrie N, Gapor A, Chambers AF, Carroll KK. Palm oil tocotrienols and plant flavonoids act synergistically with each other and with tamoxifen in inhibiting proliferation and growth of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells in culture. Asia Pac J Clin Nutr. 1997;6:41-45.

31.

Hartley CWS. The Oil Palm. 1st ed. (London, England: Longmans), p. 618, 1977.

32.

Honstra G. Beneficial Effects of Palm oil on Arterial Thrombosis (Rat) and Atherosclerosis (Rabbit). (Kuala Lumpur, Malaysia: PORIM), pp. 35-45, 1986.

33.

Irvin TT. Wound healing. Arch Emerg Med. 1985;2:3-10.

34.

Jaffri JM, Mohamed S, Rohimi N, Ahmad IN, Noordin MM, Manap YA. Antihypertensive and cardiovascular effects of catechin-rich oil palm (Elaeis guineensis) leaf extract in nitric oxide-deficient rats. J Med Food. 2011;14:775-783.

35.

Kalman DS, Schwartz HI, Feldman S, Krieger DR. Efficacy and safety of Elaeis guineensis and Ficus deltoidea leaf extracts in adults with pre-diabetes. Nutr J. 2013;12:36.

36.

Kooyenga DK, Gerler M, Watkins TR, Gapor A, Diakoumakis E, Bierenbaum ML. Palm oil antioxidant effects in patients with hyper-lipidaemia and carotid stenosis-2 year experience. Asia Pac J Clin Nutr. 1997;6:72-75.

37.

Krichevsky D. Effects of triglyceride structure on lipid metabolism. J Nutr Rev. 1988;46:177-181.

38.

Kritchevsky D, Tepper SA, Chen SC, Meijer GW. Influence of triglyceride structure on experimental atherosclerosis in rabbits. FASEB J. 1996;10:A187.

39.

Kritchevsky D. Impact of red palm oil on human nutrition and health. Food Nutr Bull. 2000;21:182-188.

40.

Kumar RS, Rajkapoor B, Perumal P. In vitro and in vivo anticancer activity of Indigofera cassioides Rottl. Ex. DC. Asian Pac J Trop Med. 2011;4:379-385.

41.

Law-Ogbomo KE, Egharevba RKA. The use of vegetable oils in the control of Callosobruchus maculatus (F) (Coleoptera: Bruchidae) in three cowpea varieties. Asian J Plant Sci. 2006;5:547-552.

42.

Lietz G, Henry CJK, Mulokozi G, Mugyabuso J, Ballart A. Use of red palm oil for the promotion of maternal vitamin A status. Food Nutr Bull. 2000;21:215-218.

43.

Manorama R, Rukmini C. Nutritional evaluation of crude palm oil in rats. Am J Clin Nutr. 1991;53:1031-1033.

44.

Marzuki A, Arshad F, Razak TA, Jaarin K. Influence of dietary fat on plasma lipid profiles of Malaysian adolescents. Am J Clin Nutr. 1991;53:1010-1014.

45.

Mattson FH, Grundy SM. Comparison of effects of dietary saturated, monounsaturated and polyunsaturated fatty acids on plasma lipids and lipoproteins in man. J Lipid Res. 1985;26:194-202.

46.

Mclntosch GH, Whyte J, McAthur R., Nestle, P. J. Barley and wheat foods; Influence on plasma cholesterol cocntrations in hypercholesterolemic men. Am J Clin Nutr. 1991;53:1205-1209.

47.

McIntyre BS, Briski KP, Gapor A, Sylvester PW. Antiproliferative and apoptotic effects of tecopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells. Proc Soc Exp Biol Med. 2000;224:292-301.

48.

Mohamed S. Oil Palm Leaf: A New Functional Food Ingredient for Health and Disease Prevention. J Food Process Technol. 2014;5:300.

49.

Naher L, Yusuf UK, Ismail A, Tan SG, Mondal MMA. Ecological status of Ganoderma and basal stem rot disease of oil palms (Elaeis guineensis Jacq.) AJCS. 2013;7:1723-1727.

50.

Nazaimoon WMW, Khalid BA. Tocotrienols-rich diet decreases advanced glycosylation end products in non-diabetic rats and improves glycemic control in Streptozotocin-induced diabetic rats. Malays J Pathol. 2002;24:77-82.

51.

Nesaretnam K, Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status. Lipids. 1998;33:461-469.

52.

Nesaretnam K, Khor HT, Ganeson J, Chong K, Gapor A. The effect of vitamin E tocotrienols from palm oil on chemically-induced mammary carcinogenesis in female rats. Nutr Res. 1992;12:879-892.

53.

Nesaretnam K, Ambra R, Selvaduray KR, Radhakrishnan A, Reimann K, Razak G, Virgili F. Tocotrienol-rich fraction from palm oil affects gene expression in tumors resulting from MCF-7 cell inoculation in athymic mice. Lipids. 2004;39:459-467.

54.

Ng TKW, Hayes KC, De Witt GF, Jegathesan M, Satgunasingham N, Ong ASH, Tan DTS. Dietary palmitic and oleic acids exert similar effects on serum cholesterol and lipoprotein profiles in normocholesterolemic men and women. J Am Coll Nutr. 1992;11:383-390.

55.

Ng TKW, Hassan K, Lim JB, Lye MS, Ishak R. Nonhypercholestrolemic effects of a palm oil diet in Malasysian volunteers. Am J Clin Nutr. 1991;53:1015S-1020S.

56.

Obahiagbon FI. A Review: Aspects of the African Oil Palm (Elaeis guineesis jacq.) and the Implications of its Bioactives in Human Health. Amer J Biochem Mol Biol. 2012;2:106-119.

57.

Obahiagbon FI, Oviasogie PO, Ukhun ME, Oviawe PN. Comparative studies of the thiamine and riboflavin contents in the sap of Raphia hookeri palm by the application of fluorimetric method and arrhenius equation. Tren Appl Sci Res. 2007;2:260-263.

58.

Obahiagbon FI, Oviasogie PO. Changes in the physicochemical characteristics of processed and stored Raphia hookeri palm sap (shelf-life studies). Am J Food Technol. 2007;2:323-326.

59.

Oguntibeju OO, Esterhuyse AJ, Truter EJ. Possible role of red palm oil supplementation in reducing oxidative stress in HIV/AIDS and TB patients: A review. J Med Pl Res. 2010;4:188-196.

60.

Oluba OM, Onyeneke CE, Ojieh GC, Eidangbe GO, Orole RT. Effects of Palm Oil Supplementation on Lipid Peroxidation and Glutathione Peroxidase Activity in Cholesterol - Fed Rats. The Internet J Cardio Res. 2009;6:1.

61.

Packer L. Interactions among antioxidants in health and disease: Vitamin E and its redox cycle. Exp Biol Med. 1992;200:271-276.

62.

Packer L, Serbinova E, Choo M. Distribution and antioxidant activity of a palm oil carotene in rats. Biochem Inter. 1992;28:881-886.

63.

Qureshi AA, Qureshi N, Wright JJ, Shen Z, Kramer G. Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols (palmvitee). Am J Clin Nutr. 1991;53;1021-1026.

64.

Qureshi A, Burger WC, Prentice N, Bird HR, Sunde ML. Regulation of Lipid metabolism in chicken liver by dietary cereals. J Nutr. 1980;110:388-393.

65.

Qureshi AA, Pearce BC, Parker RA, Deason ME. Response of hypercholesterolemic subjects to administration of tocotrienols. Lipids. 1995;30: 1171-1177.

66.

Rajoo A, Ramanathan S, Sasidharan S, Mansor SM. Standardization of Elaeis guineensis with respect to authenticity, assay and chemical constituent analysis. Afr J Biotechnol. 2010;9:7544-7549.

67.

Rasool AHG, Yuen KH, Yusoff K, Wong AR, Rahman AR. Dose dependent elevation of plasma tocotrienol levels and its effect on arterial compliance, plasma total antioxidant status, and lipid profile in healthy humans supplemented with tocotrienol rich vitamin E. J Nutr Sci Vitaminol. 2006;52:473-478.

68.

Rao BSN. Potential use of red palm oil in combating vitamin A deficiency in India. Food Nutr Bull. 2000;21:202-211.

69.

Rosalina Tan RT, Mohamed S, Samaneh GF, Noordin MM, Goh YM, Manap MYA. Polyphenol rich oil palm leaves extract reduce hyperglycaemia and lipid oxidation in STZ-rats. Int Food Res J. 2011;18:179-188.

70.

Rukmini C. Red palm oil to combat vitamin A deficiency in developing countries. Food Nutr Bull 1994;15:126-129.

71.

Runnie I, Mustapha NM, Radzali M, Azizah H, Hapizah N, Abeywardena MY, Mohamed S. Antioxidant and hypocholes-terolemic effects of Elaeis guineensis frond extract on hyper-cholesterolemic rabbits. Asean Food J. 2003;12:137-147.

72.

Salleh MN, Runnie I, Roach PD, Mohamed S, Abeywardena MY. Inhibition of low-density lipoprotein oxidation and up-regulation of low-density lipoprotein receptor in HepG2 cells by tropical plant extracts. J Agric Food Chem. 2002;50:3693-3697.

73.

Sasidharan S, Vijayarathna S. Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines. Asian Pac J Trop Biomed. 2012;2:826-829.

74.

Sasidharan S, Nilawatyi R, Xavier R, Yoga Latha L, Amala R. Wound healing potential of Elaeis guineensis Jacq leaves in an infected albino rat model. Molecules. 2010;15:3186-3199.

75.

Sasidharan S, Selvarasoo L, Latha LY. Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment. Int J Mol Sci. 2012;13:336-347.

76.

Sasidharan S, Vijayarathna S, Jothy SL, Ping KY, Latha LY. Hepatoprotective potential of Elaeis guineensis leaf against paracetamol induced damage in mice: A serum analysis. IPCBEE. 2012;39:231-234.

77.

Sasidharan S, Sharmini R, Vijayarathna S, Yoga Latha, L, Vijenthi R, Amala R, Amutha S. Antioxidant and hepatoprotective activity of methanolic extracts of Elaeis Guineensis Jacq leaf. Pharmacologyonline. 2009;3:84-90.

78.

Serbinova E, Kagan V, Han D, Packer L. Free Radical Recycling and Intramembrane Mobility in the Antioxidant properties of Alpha-tocopherol and Alpha-tocotrienol. Free Radic Biol Med. 1991;10:263-275.

79.

Solomons NW. Plant sources of vitamin A and human nutrition: red palm oil does the job. Nutr Rev. 1998;56:309-311.

80.

Song BL, DeBose-Boyd RA. Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by δ- and γ-tocotrienols. J Biol Chem. 2006;281:25054-25061.

81.

Soundararajan V, Sreenivasan S. Antioxidant activity of Elaeis guineensis leaf extract: An alternative nutraceutical approach in impeding aging. APCBEE Procedia. 2012;2:153-159.

82.

Sundram K, Khor HT, Ong SHA, Pathmanthan R. Effect of dietary palm oils on mammary carcinogenesis in female rats induced by 7, 12-dimehtlbenz (a) anthra-cene. Cancer Res. 1989;49:1447-1451.

83.

Sundram K, Hornstra G, Houwelingen AC. Replacement of dietary fat with palm oil: Effect on human serum lipid, lipropotein and apoproteins. Br J Nutr. 1992;68:677-692.

84.

Sundram K, Khor HT, Ong ASH. Effect of dietary palm oil and its fractions on rat plasma and high density lipoprotein lipids. Lipids. 1990;25:187-193.

85.

Syahmi ARM, Vijayarathna S, Sasidharan S, Latha LY, Kwan YP, Lau YL, Shin LN, Chen Y. Acute oral toxicity and brine shrimp lethality of Elaeis guineensis jacq., (oil palm leaf) methanol extract. Molecules. 2010;15:8111-8121.

86.

Tan RT, Mohamed S, Samaneh GF, Noordin MM, Goh YM, Manap MYA. Polyphenol rich oil palm leaves extract reduce hyperglycaemia and lipid oxidation in STZ-rats. Int Food Res J. 2011;18:179-188.

87.

Truswell AS, Choudhury N, Roberts DCK. Double blind comparison of plasma lipids in healthy subjects eating potato crisps fried in palmolein or canola oil. Nutr Res.1992;12:S34-S52.

88.

Van Rooyen J, Esterhuyse AJ, Engel brecht A, Toit EF. Health benefits of natural carotenoid rich oil: a proposed mechanism of protection against ischemia reperfusion injury. Asia Pac J Clin Nutr. 2008;17:316-319.

89.

Wu SJ, Liu PL, Ng LT. Tocotrienol-rich fraction of palm oil exhibits anti-inflammatory property by suppressing the expression of inflammatory mediators in human monocytic cells. Mol Nutr Food Res. 2008;52:921-929.

90.

Yamabe N, Yokozawa T, Oya T, Kim M. Therapeutic potential of (-)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats. J Pharmacol Exp Ther. 2006;319:228-236.

91.

Zhang J, Wang CR, Dai J, Chen XS, Ge KY. Palm oil diet may benefit mildly hyper cholestrerolaemic Chinese adults. Asia Pac J Clin Nutr. 1997;6:22-25.

92.

Zuzana M, Suhana M, Zalinah A, Gapor MT, Ngah WZW. Comparative effects of α-tocopherol and γ tocotrienol on lipid peroxidation status in Hep G2 cell live transfected with CYZEI gene. Eur J Sci Res.2005;7:41-56.

셀메드