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ISSN : 2287-8327

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Vol.33 No.2
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Antimicrobial activity and chemical components of two plants, Artemisia capillaris and Artemisia iwayomogi, used as Korean herbal Injin

Journal of Ecology and Environment / Journal of Ecology and Environment, (P)2287-8327; (E)2288-1220
2010, v.33 no.2, pp.141-147



& (2010). Antimicrobial activity and chemical components of two plants, Artemisia capillaris and Artemisia iwayomogi, used as Korean herbal Injin. Journal of Ecology and Environment, 33(2), 141-147.
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Abstract

This study compared the antimicrobial activity and chemical composition of two plants used as “Injin” (Korean herbal medicine), namely, Injinho (Artemisia capillaris Thunberg) and Haninjin (Artemisia iwayomogi Kitamura). The ethyl acetate and ether fractions of crude methanol extracts from A. capillaris and A. iwayomogi were tested against three grampositive bacteria (Bacillus cereus, Bacillus subtilis, Staphylococcus aureus), two gram-negative bacteria (Escherichia coli,Pseudomonas fluorescens), and a yeast (Saccharomyceus cerevisiae). The antimicrobial activity of the ethyl acetate and ether fraction of both plants was strong, but that of A. iwayomogi extracts was higher than that of A. capillaris extract for the microbes tested. The minimum inhibitory concentration of the ether and ethyl acetate fraction of A. iwayomogi was highest for P. fluorescens and lowest for S. aureus and E. coli. We analyzed the chemical composition of the ethyl acetate fraction of A. capillaris and A. iwayomogi using gas chromatography-mass spectrometry. The main components of A. capillaris and A. iwayomogi were escoparone (86.82%) and scopoletin (20.47%), respectively.

keywords
antimicrobial activity, Artemisia capillaris, Artemisia iwayomogi, escoparone, scopoletin

Reference

1.

Bauer AW, Kirby WM, Sherris JC, Turck M. 1966. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol 45: 493-496.

2.

Blum U. 1996. Allelopathic interactions involving phenolic acids. J Nematol 28: 259-267.

3.

Boussaada O, Chriaa J, Nabil R, Ammar S, Saidana D, Mahjoub MA, Chraeif I, Helal AN, Mighri Z. 2008. Antimicrobial and antioxidant activities of methanol extracts of Evax pygmaea (Asteraceae) growing wild in Tunisia. World J Microbiol Biotechnol 24: 1289-1296.

4.

Choi IH, Kim YH, Lee DN, Kim HJ. 2005. Antifungal effects of Cinamon Ramulus, Pulsatillae Radix, Dictamni Radicis Cortex, Paeoniae Radix, Arecae Semen, Artemisiae Capillaries Herba against Candida albicans. Korean J Oriental Physiol Pathol 19: 690-695.

5.

Choi SR, Ju IO, You DH, Song YE, Jang I, Ryu J. 2007. Changes of major components and growth characteristics according to harvesting times of Artemisia capillaris Thunberg. Korean J Medicinal Crop Sci 15: 189-193.

6.

Fernandez C, Monnier Y, Ormeño E, Baldy V, Greff S, Pasqualini V, Mévy JP, Bousquet-Mélou A. 2009. Variations in allelochemical composition of leachates of different organs and maturity stages of Pinus halepensis. J Chem Ecol 35: 970-979.

7.

Hammer KA, Carson CF, Riley TV. 1999. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 86: 985-990.

8.

Jang SI, Kim YJ, Lee WY, Kwak KC, Baek SH, Kwak GB, Yun YG, Kwon TO, Chung HT, Chai KY. 2005. Scoparone from Artemisia capillaris inhibits the release of inflammatory mediators in RAW 264.7 cells upon stimulation cells by Interferon-γ Plus LPS. Arch Pharm Res 28: 203-208.

9.

Kershaw L. 2000. Edible and Medicinal Plants of the Rockies. Lone Pine Publishing, Edmonton, AB.

10.

Kil BS. 1999. Allelopathic effects of Artemisia capillaris on the selected species. Korean J Ecol 22: 59-63.

11.

Kim SS, Lee CK, Kang SS, Jung HA, Choi JS. 1997. Chlorogenic acid, an antioxidant principle from the aerial parts of Artemisia iwayomogi that acts on 1,1-diphenyl-2-picrylhydrazyl radical. Arch Pharm Res 20: 148-154.

12.

Koo KA, Kwak JH, Lee KR, Zee OP, Woo ER, Park HK, Youn HJ. 1994. Antitumor and immunomodulating activities of the polysaccharide fractions from Artemisia selengensis and Artemisia iwayomogi. Arch Pharm Res 17: 371-374.

13.

Kordali S, Aslan I, Calmasur O, Cakir A. 2006. Toxicity of essential oils isolated from three Artemisia species and some of their major components to granary weevil, Sitophilus granaries (L.) (Coleoptera: Curculionidae). Ind Crops Prod 23: 162-170.

14.

Kujumgiev A, Bankova V, Ignatova A, Popov S. 1993. Antibacterial activity of propolis, some of its components and their analogs. Pharmazie 48: 785-786.

15.

Kültür S. 2007. Medicinal plants used in Kirklareli Province (Turkey). J Ethnopharmacol 111: 341-364.

16.

Lee MK, Choi GP, Ryu LH, Lee GY, Yu CY, Lee HY. 2004. Enhanced immune activity and cytotoxicity of Artemisia capillaris Thunb. extracts against human cell lines. Korean J Medicinal Crop Sci 12: 36-42.

17.

Mahasneh AM. 2002. Screening of some indigenous Qatari medicinal plants for antimicrobial activity. Phytother Res 16: 751-753.

18.

Mahasneh AM, El-Oqlah AA. 1999. Antimicrobial activity of extracts of herbal plants used in the traditional medicine of Jordan. J Ethnopharmacol 64: 271-276.

19.

Rice EL. 1984. Allelopathy. Academic Press, New York, NY.

20.

Schmidt BM, Ribnicky DM, Lipsky PE, Raskin I. 2007. Revisiting the ancient concept of botanical therapeutics. Nat Chem Biol 3: 360-366.

21.

Seo KS, Huh CK, Kim YD. 2008. Changes of biologically active components in Prunus mume fruit. Korean J Food Preserv 15: 269-273.

22.

Smith-Palmer A, Stewart J, Fyfe L. 1998. Antimicrobial properties of plant essential oils and essences against five important food-borne pathogens. Lett Appl Microbiol 26: 118-122.

23.

Song YE, Ryu JS, Chung JR, Kwak JS, Kim DH, Kim BS, Rim CW. 2001. Study on the biological activity of Artemisia iwayomogi Kitamura. Korean J Medicinal Crop Sci 9: 116-123.

24.

Wojdyło A, Oszmiański J, Czemerys R. 2007. Antioxidant activity and phenolic compounds in 32 selected herbs. Food Chem 105: 940-949.

25.

Yun KW, Jeong HJ, Kim JH. 2008. The influence of growth season on the antimicrobial and antioxidative activity in Artemisia princeps var. orientalis. Ind Crops Prod 27: 69-74.

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