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ISSN : 0376-4672
다양한 원인에 의해 발생하는 구강점막질환은 점막의 변형을 동반하기도 하고 점막의 변형없이 증상만을호소하는 경우도 있다. 점막에 병변이 나타나는 경우그 원인요소는 세균, 바이러스, 진균, 타액분비저하,음식물 등의 직접적인 요소도 있지만 복용하는 약물,면역반응, 혈액이상, 전신질환, 정신장애, 등의 간접적인 요소도 분명히 작용한다고 알려져 있다1, 2). 이중 치과재료는 구강내에 오랜시간 존재하게 되고특히 금속의 경우 마모, 부식, 용해반응으로 인하여나타나는 이온형태의 물질이 체내에 흡수되어 면역반응을 일으키거나, 구강점막에 대한 직접적이고 반복적인 접촉으로 구강내 지연형 접촉성 과민반응을 발생시킬 수 있다3, 4). 이들 점막반응은 발적부터 궤양까지다양한 형태를 보이지만 특징적인 징후가 관찰되지는않아 정확한 감별진단은 어려운 경우가 많다5, 6).
1. Sapp JP, Eversole LR, Wysocki GP. Contemporary oral and maxillofacial pathology, 1997, Clarinda Co., pp. 245-248.
2. Sharma A, Bialynicki-Birula R, Schwartz RA, Janniger CK. Lichen planus: An update and review. Cutis 2012;90:17-23.
3. McParland H, Warnakulasuriya S. Oral lichenoid contact lesions to mercury and dental amalgam-a review. J Biomed Biotechnol 2012;2012:589-569.
4. Ahlgren C, Isaksson M, Moller H, Axell T, Liedholm R, Bruze M. The necessity of a test reading after 1week to detect late positive patch test reactions in patients with oral lichen lesions. Clin Oral Investig 2013 oct 6. [Epub ahead of print]
5. Alanko K, Kanerva L, Jolanki R, Kannas L, Estlander T. Oral mucosal diseases investigated by patch testing with a dental screening series. Contact Dermatitis 1996;34:263-267.
6. Holmstrup P. Reactions of the oral mucosa related to silver amalgam: A review. J Oral Pathol Med 1991;20:1-7.
7. Vass G, Torkos A, Altmayer A et al. Epicutaneous patch test--a new diagnostic option to prevent the rejection of silicone-covered cochlear implants in children. Int J Pediatr Otorhinolaryngol 2013;77:1635-1638.
8. Cobos-Fuentes MJ, Martinez-Sahuquillo-Marquez A, Gallardo-Castillo I, Armas-Padron JR, Moreno-Fernandez A, Bullon-Fernandez P. Oral lichenoid lesions related to contact with dental materials: A literature review. Med Oral Patol Oral Cir Bucal 2009;14:e514-20.
9. Lindmaier A, Lindemayr H. Problems with dental prosthesis and dental filling materials: Results of epicutaneous tests, consequences and follow-up. Z Hautkr 1989;64:24-30.
10. Koch P, Bahmer FA. Oral lesions and symptoms related to metals used in dental restorations: A clinical, allergological, and histologic study. J Am Acad Dermatol 1999;41:422-430.
11. Dal Sacco D, Gibelli D, Gallo R. Contact allergy in the burning mouth syndrome: A retrospective study on 38 patients. Acta Derm Venereol 2005;85:63-64.
12. Bakula A, Lugovic-Mihic L, Situm M, Turcin J, Sinkovic A. Contact allergy in the mouth: Diversity of clinical presentations and diagnosis of common allergens relevant to dental practice. Acta Clin Croat 2011;50:553-561.
13. Polanco I. Celiac disease. J Pediatr Gastroenterol Nutr 2008;47 Suppl 1:S3-6.
14. 민숙진, 안형준, 박준상, 고명연. 첩포시험을 이용한 구강점막질환 환자의 접촉성 과민반응에 대한평가. 대한구강내과학회지 2002;27:159-172
15. Levi L, Barak S, Katz J. Allergic reactions associated with metal alloys in porcelain-fused-tometal fixed prosthodontic devices-A systematic review. Quintessence Int 2012;43:871-877.
16. Rasanen L, Kalimo K, Laine J, Vainio O, Kotiranta J, Pesola I. Contact allergy to gold in dental patients. Br J Dermatol 1996;134:673-677.
17. Moller H. Dental gold alloys and contact allergy. Contact Dermatitis 2002;47:63-66.
18. Stenman E, Bergman M. Hypersensitivity reactions to dental materials in a referred group of patients. Scand J Dent Res 1989;97:76-83.
19. Marino R, Capaccio P, Pignataro L, Spadari F. Burning mouth syndrome: The role of contact hypersensitivity. Oral Dis 2009;15:255-258.
20. Grushka M, Epstein JB, Gorsky M. Burning mouth syndrome. Am Fam Physician 2002;65:615-620.
21. Issa Y, Brunton PA, Glenny AM, Duxbury AJ. Healing of oral lichenoid lesions after replacing amalgam restorations: A systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98:553-565.
22. Dunsche A, Kastel I, Terheyden H, Springer IN, Christophers E, Brasch J. Oral lichenoid reactions associated with amalgam: Improvement after amalgam removal. Br J Dermatol 2003;148:70-76.
23. Mehulic M, Mehulic K, Kos P, Komar D, Katunaric M. Expression of contact allergy in undergoing prosthodontic therapy patients with oral diseases. Minerva Stomatol 2005;54:303-309.
24. Brandao GA, Simas RM, de Almeida LM et al. Evaluation of ionic degradation and slot corrosion of metallic brackets by the action of different dentifrices. Dental Press J Orthod 2013;18:86-93.
25. Mutlu-Sagesen L, Ergun G, Karabulut E. Ion release from metal-ceramic alloys in three different media. Dent Mater J 2011;30:598-610.
26. Kim YJ, Kim YK, Kho HS. Effects of smoking on trace metal levels in saliva. Oral Dis 2010;16:823-830.
27. Niki Y, Matsumoto H, Otani T et al. Screening for symptomatic metal sensitivity: A prospective study of 92 patients undergoing total knee arthroplasty. Biomaterials 2005;26:1019-1026.
28. Cadosch D, Chan E, Gautschi OP, Filgueira L. Metal is not inert: Role of metal ions released by biocorrosion in aseptic loosening--current concepts. J Biomed Mater Res A 2009;91:1252-1262.
29. Urban RM, Jacobs JJ, Tomlinson MJ, Gavrilovic J, Black J, Peoc'h M. Dissemination of wear particles to the liver, spleen, and abdominal lymph nodes of patients with hip or knee replacement. J Bone Joint Surg Am 2000;82:457-476.
30. Virgili A, Corazza M, Trombelli L, Arcidiacono A. Burning mouth syndrome: The role of contact hypersensitivity. Acta Derm Venereol 1996;76:488-490.
31. Hietanen J, Pihlman K, Forstrom L, Linder E, Reunala T. No evidence of hypersensitivity to dental restorative metals in oral lichen planus. Scand J Dent Res 1987;95:320-327.