- P-ISSN 1225-0163
- E-ISSN 2288-8985
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
Article Detail
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Investigation of Dynamic Elemental Distribution in Six Human Tissues by Neutron Activation Analysis
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2002, v.15 no.4, pp.365-372
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(2002). Investigation of Dynamic Elemental Distribution in Six Human Tissues by Neutron Activation Analysis. Analytical Science and Technology, 15(4), 365-372.
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Abstract
In this study, inorganic elemental distribution in Korean adult human tissue of liver, lung, muscle, kidney, rib and thyroid has been investigated. These tissues were collected from human's body within 48 hours after their death according to IAEA's recommended method, dried by freeze drying method and then pulverized. Neutron activation analysis was applied to these samples to determine the concentrations of 5 major elements of Ca, Mg, Na, K, and Cl and 12 trace elements of Mn, I, Sr, As, Br, Co, Cr, Cs, Fe, Rb, Se, and Zn. To confirm accuracy of analytical result was performed using three kinds of standard reference materials and resulted that the relative error is within 10% for the most of elements and the Z-score indicating a performance of analysis is within 2. The elemental distribution shows that the major elements are distributed homogeneously with a specific concentration and that the trace elements shows a distribution of different concentration with kinds of tissue and their age. Particularly, iodine shows higher concentration with 1000 <TEX>${\mu}g/g$</TEX> in thyroid, and calcium and strontium show the concentration with 15.9% and 84.4 <TEX>${\mu}g/g$</TEX> in rib, respectively.
- keywords
- Neutron Activation Analysis, human tissue, human health, trace analysis
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