- P-ISSN 1225-0163
- E-ISSN 2288-8985
- Apply for Authority
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
Article Detail
Home > Article Detail
Analytical trends in mass spectrometry based metabolomics approaches of neurochemicals for diagnosis of neurodegenerative disorders
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2017, v.30 no.6, pp.355-378
https://doi.org/10.5806/AST.2017.30.6.355
&
(2017). Analytical trends in mass spectrometry based metabolomics approaches of neurochemicals for diagnosis of neurodegenerative disorders. Analytical Science and Technology, 30(6), 355-378, https://doi.org/10.5806/AST.2017.30.6.355
- Downloaded
- Viewed
Abstract
Because neurochemicals are related to homeostasis and cognitive and behavioral functions in human body and because they enable the diagnosis of numerous neurodegenerative disorders, there has been increasing interest in the development of analytical platforms for neurochemical profiling in biological samples. In particular, mass spectrometry (MS)-based analytical methods combined with chromatographic separation have been widely used to profile neurochemicals in metabolic pathways. However, development of delicate sample preparation procedures and highly sensitive instrumental detection is necessary considering the trace levels and chemical instabilities of neurochemicals in biological samples. Therefore, in this review, analytical trends in MS-based metabolomics approaches to neurochemicals in multiple biological samples, such as urine, blood, CSF, and biological tissues, are discussed. This paper is expected to contribute to the development of an analytical platform to discover biomarkers that will aid diagnosis, prognosis, and treatment of neurodegenerative disorders.
- keywords
- neurochemicals, profiling analysis, chromatographic separation, mass spectrometry, metabolomics approach
Reference
1
1. T. Opladen, E. Cortès-Saladelafont, M. Mastrangelo, G. Horvath, R. Pons, E. Lopez-Laso, J. A. Fernández-Ramos, T. Honzik, T. Pearson, J. Friedman, S. Scholl-Bürgi, T. Wassenberg, S. Jung-Klawitter, O. Kuseyri, K. Jeltsch, M. A. Kurian and À. Garcia-Cazorla, Mol. Genet. Metab. Reports, 9, 61-66 (2016).
2
2. T. Lapainis and J. V. Sweedler, J. Chromatogr. A, 1184, 144-158 (2008).
3
3. Oliver von Bohle und Halbach and Rolf Dermietzel, Wiley-VCH, Handbook of Receptors and Biological Effects, 2006.
4
4. R. Adolfsson, C. G. Gottfries, B. E. Roos and B. Winblad, Br. J. Psychiatry., 135, 216-223 (1979).
5
5. L. F. Nolden, T. Tartavoulle and D. J. Porche, J. Nurse Pract., 10, 500-506 (2014).
6
6. E. Sánchez-López, C. Montealegre, A. L. Crego and M. L. Marina, TrAC - Trends Anal. Chem., 67, 82-99 (2015).
7
7. L. H. Rodan, K. M. Gibson and P. L. Pearl, Pediatr. Neurol., 53, 277-286 (2015).
8
8. J. Soleymani, TrAC - Trends Anal. Chem., 72, 27-44(2015).
9
9. I. A. Veselova, E. A. Sergeeva, M. I. Makedonskaya, O. E. Eremina, S. N. Kalmykov and T. N. Shekhovtsova, J. Anal. Chem., 71, 1155-1168 (2016).
10
10. D. Kondziella, Neurochem. Res., 42, 1767-1771 (2017).
11
11. C. Marecos, J. Ng and M.A. Kurian, J. Inherit. Metab. Dis., 37, 619-626 (2014).
12
12. W. T. Kassahun, Vascular., 23, 297-304 (2015).
13
13. Y. Shen, J. Lu, Q. Tang, Q. Guan, Z. Sun, H. Li and L. Cheng, Rapid, J. Chromatogr. B, 1002, 92-97(2015).
14
14. R. NAE, R. MG and T. JM, JCAR., 33, 53-55 (1982).
15
15. T. E. Dicke, M. L. Henry and J. P. Minton, J. Surg. Oncol., 34, 160-164 (1987).
16
16. Z. Wang, Q. Liang, Y. Wang and G. Luo, J. Electroanal. Chem., 540, 129-134 (2003).
17
17. J.-M. Zen, I.-L. Chen and Y. Shih, Anal. Chim. Acta, 369, 103-108 (1998).
18
18. G. Curzon and A.R. Green, Br. J. Pharmacol., 37, 689-697 (1969).
19
19. W. Wesemann, C. Grote, H. Clement, F. Block and K. Sontag, Prog. Neuropsychopharmacol. Biol. Psychiatry., 17, 487-499 (1993).
20
20. M. Karobath, J.-L. Díaz and M. O. Huttunen, Eur. J. Pharmacol., 14, 393-396 (1971).
21
21. M. Karobath, Biochem. Pharmacol., 21, 1253-1263(1972).
22
22. M. Hasanzadeh, N. Shadjou and E. Omidinia, J. Neurosci. Methods, 219, 52-60 (2013).
23
23. K. ER, S. JH and J. TM, Principles of Neural Science, 2000.
24
24. R. Rodriguez-Diaz, R. Dando, M. C. Jacques-Silva, A. Fachado, J. Molina, M. H. Abdulreda, C. Ricordi, S. D. Roper, P.-O. Berggren and A. Caicedo, Nat. Med., 17, 888-892 (2011).
25
25. I. Wessler, C. J. Kirkpatrick and K. Racké, Pharmacol. Ther., 77, 59-79 (1998).
26
26. M. B. Bhuiyan, F. Murad and M. E. Fant, Cell Commun. Signal., 4, 1-7 (2006).
27
27. K. Ofek and H. Soreq, Chem. Biol. Interact., 203, 113-119 (2013).
28
28. S. Shenhar-Tsarfaty, S. Berliner, N. M. Bornstein and H. Soreq, J. Mol. Neurosci., 53, 298-305 (2014).
29
29. J. Bergquist, A. Sciubisz, A. Kaczor and J. Silberring, J. Neurosci. Methods, 113, 1-13 (2002).
30
30. M. A. Raggi, C. Sabbioni, G. Nicoletta, R. Mandrioli and G. Gerra, J. Sep. Sci., 26, 1141-1146 (2003).
31
31. M. Tsunoda, C. Aoyama, H. Nomura, T. Toyoda, N. Matsuki and T. Funatsu, J. Pharm. Biomed. Anal., 51, 712-715 (2010).
32
32. M.-J. Kim, B.-K. Kim, S. M. Kim, J.-S. Park and J. Hong, Anal. Sci. Technol., 24(5), 319-335 (2011).
33
33. I. Marín-Valencia, M. Serrano, A. Ormazabal, B. Pérez-Dueñas, A. García-Cazorla, J. Campistol and R. Artuch, Clin. Biochem., 41, 1306-1315 (2008).
34
34. M. Yoshitake, H. Nohta, H. Yoshida, T. Yoshitake, K. Todoroki and M. Yamaguchi, Anal. Chem., 78, 920-927 (2006).
35
35. M. A. Fotopoulou and P. C. Ioannou, Anal. Chim. Acta, 462, 179-185 (2002).
36
36. T. G. Rosano, T. A. Swift and L. W. Hayes, Clin. Chem., 37, 1854-1867 (1991).
37
37. J. Bicker, A. Fortuna, G. Alves and A. Falcão, Anal. Chim. Acta, 768, 12-34 (2013).
38
38. H. W. Nam, S.-J. Park, H. S. Pyo and K. J. Paeng, Anal. Sci. Technol., 16(5), 349-357 (2003).
39
39. P.-T. Linh, S.-C. Lee, Y.-H. Kim, S.-P. Hong, C.-W. Song and J.-S. Kang, Anal. Sci. Technol., 13(5), 630-635 (2000).
40
40. K. Vuorensola and H. Sirén, J. Chromatogr. A, 895, 317-327 (2000).
41
41. R. T. Peaston and C. Weinkove, Ann. Clin. Biochem., 41, 17-38 (2004).
42
42. K. Vuorensola, J. Kokkonen, H. Sirén and R. A. Ketola, Electrophoresis, 22, 4347-4354 (2001).
43
43. M. Coen, E. Holmes, J. C. Lindon and J. K. Nicholson, Chem. Res. Toxicol., 21, 9-27 (2008).
44
44. O. Beckonert, H. C. Keun, T. M. D. Ebbels, J. Bundy, E. Holmes, J. C. Lindon and J. K. Nicholson, Nat. Protoc., 2, 2692-2703 (2007).
45
45. T. M. Tsang, B. Woodman, G. A. Mcloughlin, J. L. Griffin, S. J. Tabrizi, G. P. Bates and E. Holmes, J. Proteome Res., 5, 483-492 (2006).
46
46. M. R. Viant, B. G. Lyeth, M. G. Miller and R. F. Berman, NMR Biomed., 18, 507-516 (2005).
47
47. E. Holmes, T. M. Tsang, J. T. J. Huang, F. M. Leweke, D. Koethe, C. W. Gerth, B. M. Nolden, S.Gross, D. Schreiber, J. K. Nicholson and S. Bahn, PLoS Med., 3, 1420-1428 (2006).
48
48. M. P. Quinones and R. Kaddurah-Daouk, Neurobiol. Dis., 35, 165-176 (2009).
49
49. K. Dettmer, P. A. Aronov and B. D. Hammock, Mass Spectrom. Rewiews, 26, 51-78 (2007).
50
50. M. E. Dumas and L. Davidovic, J. Neuroimmune Pharmacol., 10, 402-424 (2015).
51
51. J.-L. Wolfender, G. Marti, A. Thomas and S. Bertrand, J. Chromatogr. A, 1382, 136-164 (2015).
52
52. B. Peng, H. Li and X. X. Peng, Protein Cell, 6, 628-637 (2015).
53
53. M. J. Nunes de Paiva, H. C. Menezes and Z. de Lourdes Cardeal, Analyst, 139, 3683-3694 (2014).
54
54. C. Silva, C. Cavaco, R. Perestrelo, J. Pereira and J. S. Câmara, Metabolites, 4, 71-97 (2014).
55
55. H. Xing, K. Zhang, R. Zhang, Y. Zhang, L. Gu, H. Shi, K. Bi and X. Chen, J. Chromatogr. B, 988, 135-142 (2015).
56
56. L. Zhao, S. Zheng, G. Su, X. Lu, J. Yang, Z. Xiong and C. Wu, J. Chromatogr. B, 988, 59-65 (2015).
57
57. J. Marcos, N. Renau, O. Valverde, G. Aznar-Laín, I. Gracia-Rubio, M. Gonzalez-Sepulveda, L. A. Pérez-Jurado, R. Ventura, J. Segura and O. J. Pozo, J. Chromatogr. A, 1434, 91-101 (2016).
58
58. J.-M. T. Wong, P. A. Malec, O. S. Mabrouk, J. Ro, M. Dus and R. T. Kennedy, J. Chromatogr. A, 1446, 78-90 (2016).
59
59. J. Chen, W. Hou, B. Han, G. Liu, J. Gong, Y. Li, D. Zhong, Q. Liao and Z. Xie, Anal. Bioanal. Chem., 408, 2527-2542 (2016).
60
60. F. Gosetti, E. Mazzucco, M. C. Gennaro and E. Marengo, Anal. Bioanal. Chem., 405, 907-916 (2013).
61
61. K. Sadilkova, K. Dugaw, D. Benjamin and R. M. Jack, Clin. Chim. Acta, 424, 253-257 (2013).
62
62. P. Hušek, Z. Švagera, D. Hanzlíková, L. Øimnáèová, H. Zahradníèková, I. Opekarová and P. Šimek, J. Chromatogr. A, 1443, 211-232 (2016).
63
63. S. Tufi, M. Lamoree, J. de Boer and P. Leonards, J. Chromatogr. A, 1395, 79-87 (2015).
64
64. Y. He, X.-E. Zhao, S. Zhu, N. Wei, J. Sun, Y. Zhou, S. Liu, Z. Liu, G. Chen, Y. Suo and J. You, J. Chromatogr. A, 1458, 70-81 (2016).
65
65. L. Zheng, X.-E. Zhao, S. Zhu, Y. Tao, W. Ji, Y. Geng, X. Wang, G. Chen and J. You, J. Chromatogr. B, 1054, 64-72 (2017).
66
66. X.-E. Zhao, Y. He, M. Li, G. Chen, N. Wei, X. Wang, J. Sun, S. Zhu and J. You, J. Pharm. Biomed. Anal., 135, 186-198 (2017).
67
67. X. Yang, Y. Hu, G. Li, and Z. Zhang, J. Sep. Sci., 8, 1380-1387 (2015).
68
68. H. He, E. Carballo-Jane, X. Tong and L. H. Cohen, J. Chromatogr. B, 997, 154-161 (2015).
69
69. N. Tohmola, O. Itkonen, U. Turpeinen, S. Joenväärä, R. Renkonen and E. Hämäläinen, Clin. Chim. Acta, 446, 206-212 (2015).
70
70. X. Li, S. Li, P. Wynveen, K. Mork and G. Kellermann, Anal. Bioanal. Chem., 406, 7287-7297 (2014).
71
71. F. Schumacher, S. Chakraborty, B. Kleuser, E. Gulbins, T. Schwerdtle, M. Aschner and J. Bornhorst, Talanta, 144, 71-79 (2015).
72
72. L. Hao, X. Zhong, T. Greer, H. Ye and L. Li, Analyst, 140, 467-475 (2015).
73
73. W. Y. Hsu, C. M. Chen, F. J. Tsai and C. C. Lai, Clin. Chim. Acta, 420, 140-145 (2013).
74
74. N. H. Park, J. Y. Hong, H. J. Shin and J. Hong, J. Chromatogr. A, 1305, 234-243 (2013).
75
75. H. J. Shin, N. H. Park, W. Lee, M. H. Choi, B. C. Chung and J. Hong, J. Chromatogr. B, 1051, 97-107(2017).
76
76. H. Lu, J. Yu, J. Wang, L. Wu, H. Xiao and R. Gao, J. Pharm. Biomed. Anal., 122, 42-51 (2016).
77
77. H. I. Woo, J. S. Yang, H. J. Oh, Y. Y. Cho, J. H. Kim, H.-D. Park and S.-Y. Lee, Clin. Biochem., 49, 573-579(2016).
78
78. M. Monteleone, A. Naccarato, G. Sindona and A. Tagarelli, Anal. Chim. Acta, 759, 66-73 (2013).
79
79. D. S. Domingues, E. J. Crevelin, L. A. B. De Moraes, J. E. C. Hallak, J. A. De Souza Crippa and M. E. C. Queiroz, J. Sep. Sci., 38, 780-787 (2015).
80
80. Q. Liang, H. Liu, T. Zhang, Y. Jiang, H. Xing and A. Zhang, RSC Adv., 6, 3586-3591 (2016).
81
81. X.-J. Zhai, F. Chen, C. R. Zhu and Y.-N. Lu, Biomed. Chromatogr., 29, 1737-1743 (2015).
82
82. C. Lv, Q. Li, X. Liu, B. He, Z. Sui, H. Xu, Y. Yin, R. Liu and K. Bi, J. Mass Spectrom., 50, 354-363 (2015).
83
83. J. Bicker, A. Fortuna, G. Alves and A. Falcão, Anal.Chim. Acta, 768, 12-34 (2013).
84
84. L. Brunelli, G. Ristagno, R. Bagnati, F. Fumagalli, R. Latini, R. Fanelli and R. Pastorelli, Metabolomics, 9, 839-852 (2013).
85
85. X. Han, M. Min, J. Wang, Z. Bao, H. Fan, X. Li, T.I. Adelusi, X. Zhou and X. Yin, J. Neurosci. Res., (2017), DOI: 10.1002/jnr.24098.
86
86. L. Konieczna, A. Roszkowska, A. Synakiewicz, T. Stachowicz-Stencel, E. Adamkiewicz-Drozyñska and T. Baczek, Talanta, 150, 331-339 (2016).
87
87. M. M. Moein, A. Abdel-Rehim and M. Abdel-Rehim, TrAC - Trends Anal. Chem., 67, 34-44 (2015).
88
88. M. M. Khamis, D. J. Adamko and A. El-Aneed, Mass Spectrom. Reviews, 36, 115-134 (2017).
89
89. D. T. Nguyen, I. S. Cho, J. W. Kim, K. R. Kim, G. Lee and M. J. Paik, Biomed. Chromatogr., 27, 216-221 (2013).
90
90. L. Konieczna, A. Roszkowska, M. Niedwiecki and T. Baczek, J. Chromatogr. A, 1431, 111-121 (2016).
91
91. B. Hashemi, P. Zohrabi, K.-H. Kim, M. Shamsipur, A. Deep and J. Hong, TrAC - Trends Anal. Chem., 97, 83-95 (2017).
92
92. I. Moreno, M. Barroso, A. Martinho, A. Cruz and E. Gallardo, J. Chromatogr. B, 1004, 67-78 (2015).
93
93. T. Rosenling, M. P. Stoop, A. Smolinska, B. Muilwijk, L. Coulier, S. Shi, A. Dane, C. Christin, F. Suits, P.L. Horvatovich, S. S. Wijmenga, L. M. C. Buydens, R. Vreeken, T. Hankemeier, A. J. Van Gool, T. M. Luider and R. Bischoff, Clin. Chem., 57, 1703-1711(2011).
94
94. J. M. T. Wong, P. A. Malec, O. S. Mabrouk, J. Ro, M. Dus and R. T. Kennedy, J. Chromatogr. A, 1446, 78-90 (2016).
95
95. L.-H. Zhang, H.-L. Cai, P. Jiang, H.-D. Li, L.-J. Cao, R.-L. Dang, W.-Y. Zhu and Y. Deng, Anal. Methods, 7, 3929-3938 (2015).
96
96. A. Wojnicz, J. Avendaño Ortiz, A. I. Casas, A.E. Freitas, M. G. López and A. Ruiz-Nuño, Clin. Chim. Acta, 453, 174-181 (2016).
97
97. W. Zhou, B. Zhu, F. Liu, C. Lyu, S. Zhang, C. Yan, Y. Cheng and H. Wei, J. Chromatogr. B, 1002, 379-386(2015).
98
98. K. Inoue, Y. Miyazaki, K. Unno, J. Z. Min, K. Todoroki and T. Toyo’oka, Biomed. Chromatogr., 30, 55-61(2016).
99
99. M. S. S. Bergh, I. L. Bogen, E. Lundanes and Å. M. L. Øiestad, J. Chromatogr. B, 1028, 120-129 (2016).
100
100. F. Kondo, M. Tachi, M. Gosho, M. Fukayama, K. Yoshikawa and S. Okada, Anal. Bioanal. Chem., 407, 5261-5272 (2015).
101
101. S. Greco, W. Danysz, A. Zivkovic, R. Gross and H. Stark, Anal. Chim. Acta, 771, 65-72 (2013).
102
102. P. Voehringer, R. Fuertig and B. Ferger, J. Chromatogr. B, 939, 92-97 (2013).
103
103. X.-E. Zhao, Y. He, P. Yan, N. Wei, R. Wang, J. Sun, L. Zheng, S. Zhu and J. You, RSC Adv., 6, 108635-108644 (2016).
104
104. A. Gottås, Å. Ripel, F. Boix, V. Vindenes, J. Mørland and E. L. Øiestad, J. Pharmacol. Toxicol. Methods, 74, 75-79 (2015).
105
105. R. Nirogi, P. Komarneni, V. Kandikere, R. Boggavarapu, G. Bhyrapuneni, V. Benade and S. Gorentla, J. Chromatogr. B, 913–914, 41-47 (2013).
106
106. X. S. Li, S. Li and G. Kellermann, J. Chromatogr. A, 1449, 54-61 (2016).
107
107. T. M. Fonseka, X.-Y. Wen, J. A. Foster and S. H. Kennedy, J. Neurosci. Res., 94, 3-14 (2016).
108
108. A. Aragon, J. Legradi, A. Ballesteros-Gómez, J. Legler, M. van Velzen, J. de Boer and P. Leonards, Anal. Bioanal. Chem., 409, 2931-2939 (2017).
109
109. S. Lista, H. Zetterberg, B. Dubois, K. Blennow and H. Hampel, J. Neurol., 261, 1234-1243 (2014).
110
110. R. González-Domínguez, A. Sayago and Á. Fernández-Recamales, J. Chromatogr. B, (2017) DOI: 10.1016/j.jchromb.2017.02.008.
111
111. M. M. Koek, R. H. Jellema, van der J. Greef, A.C. Tas and T. Hankemeier, Metabolomics, 7, 307-328(2011).
112
112. K. K. Pasikanti, P. C. Ho and E. C. Y. Chan, J. Chromatogr. B, 871, 202-211 (2008).
113
113. P. S imek, P. Hus k and H. Zahradníèková, Anal. Chem., 80, 5776-5782 (2008).
114
114. N. A. Alterman and P. Hutzinger, In ‘Amino acid handbook’, Chapter 13, Springer, New York, 2012.
115
115. M.-J. Paik, D.-T. Nguyen, J. Yoon, H. S. Chae, K.-R. Kim, G. Lee and P. C. Lee, Bull. Korean Chem. Soc., 32, 2418-2422 (2011).
116
116. K.-R. Kim, H.-G. Park, M.-J. Paik, H.-S. Ryu, K.S.Oh, S.-W. Myung and H. M. Liebich, J. Chromatogr. B., 712, 11-22 (1998).
117
117. M.-J. Paik, E.-Y. Cho, H. Kim, K.-R. Kim, S. Choi, Y.-H. Ahn and G. Lee, Biomed. Chromatogr., 22, 450-453 (2008).
118
118. M.-J. Paik, H.-J. Lee and K.-R. Kim, J. Chromatogr. B, 821, 94-104 (2005).
119
119. M.-J. Paik and K.-R. Kim, J. Chromatogr. A, 1034, 13-23 (2004).
120
120. S. T. Kadam and S. S. Kim, J. Organomet. Chem., 694, 2562-2566 (2009).
121
121. M. Sano, V. Ferchaud-Roucher, C. Nael, A. Aguesse, G. Poupeau, B. Castellano and D. Darmaun, J. Mass Spectrom., 49, 128-135 (2014).
122
122. Ø. Midttun, G. Kvalheim and P. M. Ueland, Anal. Bioanal. Chem., 405, 2009-2017 (2013).
123
123. W. Lee, N. H. Park, T.-B. Ahn, B. C. Chung and J. Hong, J. Chromatogr. A, (2017), DOI: 10.1016/j.chroma.2017. 10.021.
124
124. S. Jiang, Z. Liang, L. Hao and L. Li, Electrophoresis, 37, 1031-1038 (2016).
125
125. H. Chu, A. Zhang, Y. Han, S. Lu, L. Kong, J. Han, Z. Liu, H. Sun and X. Wang, J. Chromatogr. B, 1015-1016, 50061 (2016).
Other articles from this issue
- Development of latent footwear impression on porous surfaces using DL-alanine solution and 1,2-indanedione solution
- The shelf life of 1,2-indandione/zinc and polyvinylpyrrolidone solutions used to develop latent fingermarks deposited on the surface of thermal paper
- Introduction of a novel swabbing material of a wiper and establishment of an optimal method for the collection of organic explosive residues
- Paint booth volatile organic compounds emissions in an urban auto-repair center
- Decomposition characteristics of pollutants by time dependent variation of livestock carcass leachate
- Proteomic analysis of Korean mothers' human milk at different lactation stages; postpartum 1, 3, and 6 weeks
- Analytical trends in mass spectrometry based metabolomics approaches of neurochemicals for diagnosis of neurodegenerative disorders
- Determination of isoquinoline alkaloids by UPLC-ESI-Q-TOF MS: Application to Chelidonium majus L.
- Analytical trends on screening of illegal adulterants in supplementary diets
- Comparative analysis of detonation velocity in determining product composition for high energetic molecules using stoichiometric rules
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.