- P-ISSN 1225-0163
- E-ISSN 2288-8985
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
논문 상세
Home > 논문 상세
Evaluation of extraction methods for essential oils in mugwort (Artemisia montana) using gas chromatography-mass spectrometry
분석과학 / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2022, v.35 no.2, pp.53-59
https://doi.org/10.5806/AST.2022.35.2.53
(Woosuk University)
(College of Pharmacy, Woosuk University)
(College of Pharmacy, Woosuk University)
(Department of Pharmaceutical Engineering, Cheongju University)
(우석대학교)
(College of Pharmacy, Woosuk University)
(College of Pharmacy, Woosuk University)
(College of Pharmacy, Woosuk University)
(College of Pharmacy, Woosuk University)
(Department of Pharmaceutical Engineering, Cheongju University)
(우석대학교)
(College of Pharmacy, Woosuk University)
(College of Pharmacy, Woosuk University)
Jihwan,
K.
,
Si-Eun,
O.
,
Eunjung,
C.
,
Sung-Hoon,
L.
,
황인현,
Ju-Young,
K.
,
&
이원웅.
(2022). . 분석과학, 35(2), 53-59, https://doi.org/10.5806/AST.2022.35.2.53
- 다운로드 수
- 조회수
Abstract
Mugwort (Artemisia montana), which is a perennial plant mainly distributed throughout Northeast Asian regions, has been used as a preferred source of various foods and traditional medicines in Korea. In particular, as essential oils extracted from mugwort were reported to be biologically active, its steam distillate has been widely used to treat various conditions, such as itching, hemorrhoids, and gynecological inflammation. Therefore, efforts have been devoted to develop effective methods for the collection of bioactive essential oils from mugwort. In this study, five mugwort extracts were obtained using different extraction conditions, namely, 6 % ethanol at room temperature and at 80 °C, pure ethanol, n-hexane, and an adsorbent resin. To evaluate the five extracts of mugwort, area-under-the-curve values (AUCs), chemical profiles, and major bioactive essential oil contents were investigated using gas chromatography-mass spectrometry (GC-MS). An overall assessment of the volatile components, including essential oils, in the five extracts was conducted using AUCs, and the individual essential oil in each extract was identified. Furthermore, the four major essential oils (1,8- cineole, camphor, borneol, and α-terpineol), which are known to possess anti-microbial and anti-inflammatory activities, were quantified using authentic chemical standards. Based on the evaluation results, pure ethanol was the best extractant out of the five used in this study. This study provides evaluation results for the five different mugwort extracts and would be helpful for developing extraction methods to efficiently collect the bioactive oil components for medical purposes using chemical profiles of the extracts.
- keywords
- mugwort, Artemisia montana, essential oils, extraction method, chemical profile, gas chromatography, mass spectrometry
참고문헌
1
1 S.-N. Ryu and S. S. Kang, Korean J. Crop Sci., 49, 169-175 (2004).
2
2. J.-C. Park, Y.-B. Yu, J.-H. Lee and N.-J. Kim, J. Korean Soc. Food Nutr., 23(1), 116-119 (1994).
3
3. Y.-S. Kim, J.-H. Lee, M.-N. Kin, W.-G. Lee and J.-O. Kim, J. Korean Soc. Food Nutr., 23(2), 261-267 (1994).
4
4. C. Yun, Y. Jung, W. Chun, B. Yang, J. Ryu, C. Lim, J.-H. Kim, H. Kim and S.-I. Cho, Mediators Inflammation, 2016, 1-8 (2016).
5
5. J.-D. Cha, M.-R. Jeong, H.-J. Choi, S.-I. Jeong, S.-E. Moon, S.-I. Yun, Y.-H. Kim, B.-S. Kil and Y.-H. Song, Planta Med., 71, 575-577 (2005).
6
6. H.-T. Trinh, I.-A. Lee, Y.-J. Hyun and D.-H. Kim, Planta Med., 77, 1996-2002 (2011).
7
7. M.H. Park, M.-J. Kim, W.-I. Cho, P.-S. Chang and J. Lee, Korean J. Food Sci. Technol., 41(5), 587-591 (2009).
8
8. M.-S. Chung, Korean J. Food Cookery Sci., 26(6), 840-847 (2010).
9
9. G. Wenqiang, L. Shufen, Y. Ruixiang and H. Yanfeng, Nat. Prod. Res., 20(11), 992-998 (2006).
10
10. M. E. Lucchesi, F. Chemat and J. Smadja, J. Chromatogr. A, 1043, 323-327 (2004).
11
11. H.-B. Yuan, L.-N. Shang, C.-Y. Wei and B.-Z. Ren, Chem. Res. Chin. Univ., 26(6), 888-892 (2010).
12
12. M. Z. Ozel and H. Kaymaz, Anal. Bioanal. Chem., 379, 1127-1133 (2004).
13
13. T. Fornari, G. Vicente, E. Vázquez, M. R. García-Risco and G. Reglero, J. Chromatogr. A, 1250, 34-48 (2012).
14
14. J. Y. Choi, I.H. Cho, Y. S. Kim and H. J. Lee, J. Korean Soc. Appl. Biol. Chem., 57, 323-329 (2014).
15
15. K. Umano, Y. Hagi, K. Nakahara, A. Shoji and T. Shibamoto, J. Agric. Food Chem., 48, 3463-3469 (2000).
16
16. Y.-Z. Liang, P. Xie and K. Chan, J. Chromatogr. B, 812, 53-70 (2004).
17
17. M. Hudaib, E. Speroni, A. M. D. Pietra and V. Cavrini, J. Pharm. Biomed. Anal., 29, 691-700 (2002).
18
18. A. Man, A. S. Gâz, A. D. Mare and L. Berta, Rev. Rom. Med., 25, 335-343 (2017).
19
19. P. M. Bohra, A. S. Vase and V. G. Pangarkar, J. Chem. Tech. Biotechnol., 60, 97-102 (1994).
20
20. P. K. Rout, Y. R. Rao, O. Prakash and P. Khare, Asia-Pac. J. Chem. Eng., 10, 659-669 (2015).
권호 내 다른 논문
- Enhanced ion-exchange properties of clinoptilolite to reduce the leaching of nitrate in soil
- Evaluation of extraction methods for essential oils in mugwort (Artemisia montana) using gas chromatography-mass spectrometry
- Development and validation of an analytical method to quantify baphicacanthin A by LC-MS/MS and its application to pharmacokinetic studies in mice
- Development of an efficient method of radiation characteristic analysis using a portable simultaneous measurement system for neutron and gamma-ray
- Determination of Grayanotoxin I and Grayanotoxin III in mad honey from Nepal using liquid chromatography-tandem mass spectrometry
- more
추천 논문
학술지 홈페이지 이용 환경은 크롬 브라우저 사용을 권장합니다.