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  • P-ISSN 1225-0163
  • E-ISSN 2288-8985

Characterization of Adsorbents for the Simultaneous Solid-Phase Extraction of Trace <TEX>$\beta$</TEX>-Blockers from Biological Samples

Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1993, v.6 no.4, pp.375-381
Kim, Kyoung Rae
Kim, Do Jeong
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Abstract

The efficiencies of four different solid absorbents were evaluated for the simultaneous solid-phase extraction of six <TEX>${\beta}$</TEX>-blockers from biological sample. Chromosorb 107 using methanol as the eluting solvent gave the highest solid-phase extraction yield. From the breakthrough studies of <TEX>${\beta}$</TEX>-blockers, the excellent sorption and desorption properties of the Chromosorb 107 column were verified. The usefulness of Chromosorb 107/methanol was examined for the simultaneous solid-phase extraction of the <TEX>${\beta}$</TEX>-blockers from serum in the concentration range of 2~8ppm.

keywords
solid-phase extraction, <TEX>${\beta}$</TEX>-blockers, Chromosorb 107/methanol, breakthrough curve, serum


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