- P-ISSN 1225-0163
- E-ISSN 2288-8985
The efficiencies of four different solid absorbents were evaluated for the simultaneous solid-phase extraction of six <TEX>${\beta}$</TEX>-blockers from biological sample. Chromosorb 107 using methanol as the eluting solvent gave the highest solid-phase extraction yield. From the breakthrough studies of <TEX>${\beta}$</TEX>-blockers, the excellent sorption and desorption properties of the Chromosorb 107 column were verified. The usefulness of Chromosorb 107/methanol was examined for the simultaneous solid-phase extraction of the <TEX>${\beta}$</TEX>-blockers from serum in the concentration range of 2~8ppm.