- P-ISSN 1225-0163
- E-ISSN 2288-8985
- Apply for Authority
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
Article Detail
Home > Article Detail
Determination of Memantine HCl by UV Spectrophotometry using MPCN as an UV-labelling Reagent
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1993, v.6 no.4, pp.405-409
Jang,
S., Choi,
J., &
Yoo,
G.
(1993). Determination of Memantine HCl by UV Spectrophotometry using MPCN as an UV-labelling Reagent. Analytical Science and Technology, 6(4), 405-409.
- Downloaded
- Viewed
Abstract
Spectrophotometric assay for memantine HCl was developed by using sodium 1-(4-methoxypheyl) cinnamonitrile-2-sulfonate (MPCN) as an UV labelling reagent. The optimum derivatizing condition was obtained by incubation for 30 min at pH 5.0 in the presence of 20-fold molar excess of the labelling reagent. The absorbance of reaction product was measured at 324.5 nm and detection limit was <TEX>$0.43{\mu}g/ml$</TEX>. A linear range was <TEX>$5.0{\times}10^{-6}{\sim}6.5{\times}10^{-5}M$</TEX> of memantine HCl. The linear regression analysis of absorbance at various drug concentration was r
- keywords
- Spectrophotometric assay, memantine HCl, sodium 1-(4-methoxyphenyl) cinnamonitrile-2-sulfonate (MPCN), UV labelling reagent
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- An Analytical Method of Thromboxane <TEX>$B_2$</TEX> by Fast Atom Bombardment Mass Spectrometry
- Optimization of Parameters for Simultaneous Multielemental Analysis by Atomic Absorption Spectrometry
- Determination of blood lead concentration by the atomic absorption spectrometry with graphite furnace-Comparison of blood lead concentration between occupationally exposed workers and control group
- Study on the Plasma Oscillation for Gas Chromatographic detector
- Characterization of Adsorbents for the Simultaneous Solid-Phase Extraction of Trace <TEX>$\beta$</TEX>-Blockers from Biological Samples
- Retention Behavior of Organic Compounds on Reversed-Phase Column expected by Van der Waals Volume
- Study on the process of Sanguisorbae radix
- Analysis of Alkaloids in Uncaria Hooks
- Characteristic Component of Rehmanniae Radix Preparata Compared to Rehmanniae Radix and Rehmanniae Radix Crudus
- Determination of Memantine HCl by UV Spectrophotometry using MPCN as an UV-labelling Reagent
- DERIVATIZATION OF FATTY ACIDS WITH 2-BROMOACETYLTRIPHENYLENE FOR HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.