- P-ISSN 1225-0163
- E-ISSN 2288-8985
The determination method of 2-mercapto-1-methyl-imidazole(MMI) in <TEX>$5.0{\times}10^{-2}M$</TEX> lithium perchlorate solution has been investigated by the differential pulse polarography. The optimum conditions for the determination of MMI were as fellows; -0.9 volt(vs. Ag/AgCl) initial potential, 80mV pulse height, 2mV/sec scan rate, and medium mercury drop size. The calibration curve showed a good linearlity in the range of <TEX>$1.0{\times}10^{-7}M$</TEX> to <TEX>$8.0{\times}10^{-5}M$</TEX> and the detection limit was <TEX>$2.2{\times}10^{-9}M$</TEX>. This method was applicable to the determination of MMI in thyroid drugs without interference from the additives.