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The Optimum Conditions for the Simultaneous Determination of Neurotransmitters in Rat Brain Striatum by High Performance Liquid Chromatography with Electrochemical Detection
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1995, v.8 no.2, pp.215-220
Kang,
J., Mun,
M., Shin,
H., &
Lee,
S.
(1995). The Optimum Conditions for the Simultaneous Determination of Neurotransmitters in Rat Brain Striatum by High Performance Liquid Chromatography with Electrochemical Detection. Analytical Science and Technology, 8(2), 215-220.
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Abstract
A simple, efficient and sensitive method was described for the simultaneous determination of catecholamine, indoleamine and related metabolites from the homogenates of the rat brain striatum by HPLC-ECD. The optimum mobile phase on a reverse phase <TEX>$C_{18}$</TEX> column was 35mM sodium acetate buffer(included 10mM citric acid, 0.13mM <TEX>$Na_4EDTA$</TEX>, 0.58mM SOS, pH3-4):MeOH
- keywords
- HPLC-ECD, optimum conditions, catecholamines, indoleamines, neurotransmitters, metabolites, striatum
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