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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

The Clinical Effects of Gamichuongsangboha-tang (Jiaweiqingshangbuxia-tang)extract in Asthmatic Patients Based on Severity

Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2004, v.25 no.2, pp.110-118







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Abstract

Objectives : Based on the changes of quality of life and pulmonary function test, we aimed to identify the effect of Gamichuongsangboha-tang and the side effects of Gamichuongsangboha-tang in asthmatic patients. Materials and Methods : The subjects are consisted of 30 patients with asthma had been treated with Gamichuongsangboha-tang extract, for four weeks. Gamichuongsangboha-tang extract is the extracted powder form of modified herbal decoction, Chuongsangboha-whan which has been used of the traditional therapeutic agent of asthma. Pulmonary function test(PFT) was checked before and after 4week treatments. Quality of Life Questionnaire for Adult Korean Asthmatics(QLQAKA) was checked before and after 2week, 4week treatments. Unpleasant symptoms were checked in all patients at 2 weeks and 4 weeks from the begining of medication. Results : Treatment by Gamichuongsangboha-tang extract for four weeks resulted in significant increase in FEV1.0%, PEFR%, QLQAKA. The total efficacy rate of QLQAKA in the patient group was 53.3% after 4weeks. The QLQAKA of the step2, step3, step4 group(n=18, 55.6%) classified by Global initiative for asthma(GINA) consistently increased, and significantly improvement of QLQAKA occured in step3 group. In step4 group, FEV1.0%, and PEFR% were significantly increased. Total 15 patients had exprienced unpleasant symptoms during 2week-medication, however these symptoms disappeared all but 2 cases with no need of further treatment during next 2 week-medicaion. Conclusions : This study shows that Gamichuongsangboha-tang extract has the effects on improvement of pulmonary function and quality of life, especially in persistent symptomatic asthmatics. Obviously further researches concerning all these are still necessary.

keywords
Gamichuongsangboha-tang(Jiaweiqingshangbuxia-tang), Asthma, Pulmonary Function Test(PFT), Quality of Life(QOL), Severity, Gamichuongsangboha-tang(Jiaweiqingshangbuxia-tang), Asthma, Pulmonary Function Test(PFT), Quality of Life(QOL), Severity


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