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  • P-ISSN 1225-0163
  • E-ISSN 2288-8985

A study on Chemical Constituents from Marine Sponge Luffariella sp.

Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1996, v.9 no.4, pp.355-363
Park, Sun Ku
Kim, Taek Jae
Cho, Hyun-Woo
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Abstract

The two metabolites, Aaptamine(1) and Demethyl(oxy)aaptamine(2) were isolated from marine Sponge Luffariella sp., collected in October 1992, Manado Bay, Sulawesi in Indonesia showed in vitro activity against KB cancer cell line. Their structures were elucidated by <TEX>$^1H-$</TEX>, <TEX>$^{13}C-NMR$</TEX>, <TEX>$^1H-^{13}C$</TEX>(1 bond) heteronuclear multiple quantum coherence spectroscopy(HMQC), electron ionization mass spectroscopy(EIMS), ultra-violet spectroscopy(UV) and infrared spectroscopy(IR).

keywords
Luffariella sp., Aaptamine, Demethyl(oxy)aaptamine, Spectroscopic method, Flash Column Chromatography


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