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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

A PILOT STUDY TO ASSESS THE EFFECT OF GAMI-JIWHANG-TANG ON COGNITIVE EFFECTS IN HEALTHY CHILDREN

Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2004, v.25 no.4, pp.129-138
Geon-Ho Bahn


Yong-Hee Kim
Eun-Kyung Paik (Haema Oriental Medical Clinic)
Jae-Hyung Park (Haema Oriental Medical Clinic)
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Abstract

Objectives: Treatments for patients with mental retardation and pervasive developmental disorders are not curative, and are designed to help those with disabilities adjust to their environments and daily demands. As clinicians, the present authors tried to find agents with potentially curative properties. Among the numerous herbal formulations available, we chose and assessed Gami-jiwhang-tang (GJT) in the hope that it would improve cognitive development of children. Methods: Subjects were typically-developing healthy, 7- to 8-year-old boys and girls living in Seoul, Korea. The experimental group took GJT for six weeks and was followed up six weeks after discontinuation of GJT. The control group was assessed at the same intervals but did not receive placebos. To measure the effects of GJT, neuropsychological tests and intelligence test were taken before commencing GJT and twelve weeks later. Results: For all of the ANOVAs, the treatment by time interaction terms was not significant. However, the experimental group showed the tendency to be progressed in most subscales compared with the control group, especially on performance intelligence, visual organization, and verbal fluency. Conclusion: Although GJT failed to reveal significant improvement in cognition, we remain hopeful about the compound and believe that it should be evaluated by a double-blind, placebo-controlled trial in the future.

keywords
Gamijiwhangtang intelligence cognition children herbal medicine, Gamijiwhangtang intelligence cognition children herbal medicine


Reference

1

(1992) and Systems of Supports American Association on Mental Retardation,

2

(2003) Individuals with mental retardation.. Pediatric psychopharmacology: Principles and Practice, Oxford University Press,

3

(Oct,2000) Effect of Liuweidihuang-tang-jia-wei forintelligence in healthy children. Enhancing the evidence-base for TCM practice-Methodology and Grantsmanship,

4

(2002) Effect of Liuweidihuang-tang on alcohol-induced decrease in new cell formation in rat dentate gyrus,

5

(1967) Developmental Test of Visual-Motor Integration, Follett Publishing Company

6

(1982) and teaching manual for the Developmental Test of Visual-Motor Integration, Modern Curriculum Press

7

(2003) Polygonum multiflorum extracts improve cognitive performance in senescence accelerated mice,

8

(1999) The combined therapy of Eastern and Western Medicine,

9

(1972) Human memory and medical temporal region of the brain, Unpublished PhD thesis McGill University

10

(1998) Effects of fluoxetine treatment in young children with idiopathic autism,

11

(1998) Trends in alternative medicine use in the United States,

12

(1998) Neurogenesis in the adult human hippocampus,

13

(2002) A retrospective open trial of adjunctive donepezil in children and adolescents with autistic disorder,

14

(1961) Distinctive features of learning in the higher animal, Oxford University Press

15

(2002) Fluoxetines effects on cognitive performance in patients with traumatic brain injury,

16

(1995) Dong-E-Bo-Gam,

17

(2000) Effects of Yukmi on the liver of Senescence Accelerated Mice(SAM) exposed to oxidative stress,

18

(2002) Shenqi-wan increases cell proliferation of cultured hippocampal cell line HiB5 and dentate gyrus of young Sprague-Dawley rats ,

19

A literature review of Yukmijiwhangwan for the treatment of children The Korean Journal of Oriental Pediatrics 1990;4,

20

(1996) A literatural study on the YukMiGiHwangTang ,

21

(2003) The ameliorating effects of cognition-enhancing Chinese herbs on scopolamine- and MK-801-induced amnesia in rats,

22

Study of treatment on acquired infantile mental retardation with traditional Chinese and Western medicine,

23

(2003) Autistic and Other Pervasive Developmental Disorders., Oxford University Press

24

(1997) Use of alternative health care practitioners by Canadians,

25

(1980) Complementary functional specializations of the human cerebral hemisphere,

26

(1999) Handbook of normative data for neuropsychological assessment, Oxford University Press

27

(2002) Whats in a name? A systematic review of the nomenclature of Chinese medical formulae,

28

(1991) Korean Educational Development Institute Wechsler Intelligence Scale for Children,

29

(amjpsychiatry1989;146194-199) The UCLA-University of Utah epidemiologic survey of autism,

30

(2003) Protective effect of shenqi-wan against H2O2-induced apoptosis in hippocampal neuronal cells,

31

(1995) Composite acupuncture treatment of mental retardation in children,

32

(1943) The Chicago tests of primary mental abilities,

33

(2000) Mental disorders and the use of alternative medicine Results from a national survey,

34

(1998) Liu-Wei-Dihuang:A study by pulse analysis,

35

75 infantile palsy children treated with acupuncture, acupressure and functional training., acupressure and functional training

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