- P-ISSN 1010-0695
- E-ISSN 2288-3339
- 권한신청
- P-ISSN1010-0695
- E-ISSN2288-3339
논문 상세
Home > 논문 상세
Screening for Various Herb Medicines Extracts against HSV-1,2
대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2004, v.25 no.4, pp.180-187
(동국대학교)
Seong-Woo,
L.
(2004). . 대한한의학회지, 25(4), 180-187.
- 다운로드 수
- 조회수
Abstract
In order to find antiviral compounds against Herpes simplex virus type Ⅰ(HSV-1) and Herpes simplex virus type Ⅱ(HSV-2) from herb medicines, a convenient virus-induced cytopathic effect (CPE) inhibition assay was introduced. Forty-four purchased herbal medicines, and their toxicity of infected cell and anti-viral activities were evaluated. Among them, the major part of herbal medicines showed cell stability compared with the contrast. Cytotoxic concentration (CC) of the H2O extracts of Sanpoongkosamwhan against HSV-1 and HSV-2 was 18.5, Chonyolchesuptang against HSV-1 and HSV-2 was 13.1, Whangyonhaedoktang against HSV-1 and HSV-2 was 15.3, Hyongbangpaedoksan against HSV-1 and HSV-2 was 9.3. These are high level cytotoxic concentration compared with the contrast. Therefore, we assumed that the high level cytotoxic concentration of various herbal medicines play a major role in improvement of antiviral activity at the first infective cell. But the antiviral effect was not determined for selective index (SI)=CC50/EC50. The other herbal medicines were not determined to show potent anti-HSV 1,2 activity. The antiviral activation using herbs in this thesis have unlimited objects, to select research objects that will help to show a direction for antiviral drug development that will have fewer side effects and more excellent efficiency.
- keywords
- Anti-viral effect, Herb Medicines, Screening, Herpes simplex virus type Ⅰ (HSV-1), Herpes simplex virus type Ⅱ(HSV-2), Anti-viral effect, Herb Medicines, Screening, Herpes simplex virus type Ⅰ (HSV-1), Herpes simplex virus type Ⅱ(HSV-2)
참고문헌
1
(1990) An investigation of pathology symptom and treatment on AIDS compared oriental medicine with western medicine,
2
(1995) Duck hepatitis B model for screening of antiviral agents from medicinal herbs,
3
(1992) Uses of hepatitis B virus polymerase and reserve transscriptase in the evaluation of anti-hepatitis B virus drugs,
4
(1994) Screening anti-HIV Chinese material media with HIV and equine infectious anemic virus reverse transcripts,
5
(1992) Mechanism of inhibition of HIV-1 infection in vitro by purified of Prunella vulgaris,
6
(1989) Inhibition of the pseudorabies virus by an antiviral agent isolated from the leaves of Melia Azedarach,
7
(1991) antiviral and immunopotentiating activies of pine cone extracts potential medicinal efficiency of natural and synthetic lignin-related materials,
8
(1994) Screening of Epstein-Barr virus early antigen expression inducers from Chinese medical herbs and plants,
9
(1994) Minireview trichosantin-a protein with multiple pharmacological properties,
10
(1997) Anti-herpetic Activity of Various Plant Extracts,
11
(1996) Study on the Anti-HSV Activity of Korean Traditional Prescriptions( Herb complexes) ,
12
(1995) Study on the Anti-HSV Activity of Natural complex Products Jounal of Korean Oriental Medicine Institute,
13
(1993) The pharmacology of Chinese Herbs University of Louisville,
14
(1992) Korea Rearch Institute of Chemical Technology The research of medical practice and pharmaceutical dispensing screening technique,
15
(1996) Medicalmicrobiology, Hyunmoon publishing company
16
(1989) HIV with reduced sensicivity to zidovudine isolated during prolonged therapy,
17
(1988) Effect of continuous intravenous infusion of zidovudine in children with symptomatic HIV infection,
18
(1978) Thymidine kinase from herpes simplex virus phosphorate the new anti-viral compound 9-,
- 다운로드 수
- 조회수
- 0KCI 피인용수
- 0WOS 피인용수
권호 내 다른 논문
- Effect of Do-In (Prunus persica L. BATSCH) Water Extract (PPE) on Concentration of Extracellular Acetylcholine in the Rat Hippocampus
- The Anti-nociceptive and Anti-inflammatory Effect of Achyranthes Japonica Nakai
- Effects of Bambusae concretio Silicea on Suppression of Collagenolysis and Bone Resorption in Mouse Calvarial Osteoblasts
- Inhibitory effects of transforming growth factor and Drynariae Rhizoma on leukocytosis associated with the chronic phase of arthritis in mice
- Study on the Relationship between Polymorphisms in Glutathione S-transferase and Ischemic Cerebrovascular Disease
- Correlation between Obesity and Lumbar Lordosis in Obese Pre-Menopausal Korean Females
- Effect of Saenggitang on Learning and Memory Ability in Mice
- Experimental Studies on the Effect of Gamibaegi-eum
- Cytotoxic effects of ethanol extracts of Saussurea lappa mediated by mitochondrial apoptotic pathway
- Effects of Panax Ginseng on the Sperm Motility and Spermatogenesis in the SD Rat
- Paeonia radix decreases intracerebral hemorrhage-induced neuronal cell death via suppression on caspase-3 expression in rats
- Inhibition of cell growth and induction of apoptosis by Euonymus alatus (Thunb.) Sieb in human leiomyomal smooth muscle cells
- Susceptibility of Oral Bacteria to Essential Oil of Artemisia capillaris Thunb
- A PILOT STUDY TO ASSESS THE EFFECT OF GAMI-JIWHANG-TANG ON COGNITIVE EFFECTS IN HEALTHY CHILDREN
- A PILOT STUDY FOR DEVELOPING AN ASSESSMENT SCALE FOR THE EFFECT OF HERBAL MEDICINE IN HEALTHY CHILDREN: OPEN-LABEL STUDY WITH GAMI-JIWHANGTANG
- Identification of Angelica Species by Pyrosequencing
- Analysis of Survival in 273 Terminally Ill Cancer Patients Treated with Traditional Oriental Therapies
- Effects of Armillaria mellea Extract on Macrophage and NK Cell Activity
- A Study on the Clinical Features of Ordinary Sleeping Patterns Based on the Sasang Constitution, Using the Logistic Regression
- Screening for Various Herb Medicines Extracts against HSV-1,2
- Novel Therapeutic Approach toward Inflammatory Diseases: Targeting Transglutaminase 2
- Effects of Palmijihwangtang (PMT) and Exercise on Glucose Metabolism in Myocardium Cell Membrane and Pancreas β-Cell of Zucker Diabetic Fatty Rats
- Study on the Relationship between Candidate Genes of Cerebral Infarction and Sasang Constitution
- A Clinical Study of Electroacupuncture on an Overactive Bladder
- A Case Report for One Case of Thyrotoxic Periodic Paralysis Patient
- more
추천 논문
학술지 홈페이지 이용 환경은 크롬 브라우저 사용을 권장합니다.