The beginning of digitization activities in the National Library of the Czech Republic are interconnected with the first periods of existence of the UNESCO Memory of the World programme. It was in 1992 when the library accepted the UNESCO proposal to prepare a pilot CD-ROM publication for the programme showing the most precious items from its collections. In 1993 - 1995, the publication was followed by two another titles, which presented two medieval manuscripts in their entirety, providing both all the image documentation and scientific description of various features of the original documents. The digitization centre specialized in processing of old manuscripts and old printed books in co-operation with the Czech AIP Beroun Company. Nowadays, these two national programmes in which dozens of Czech and also several foreign institutions take part - are represented on their access side by two digital libraries: Manuscriptorium and Kramerius.