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  • P-ISSN 1225-0163
  • E-ISSN 2288-8985

Bromide Concentration in Human Biological Samples Intoxicated by Methylbromide

Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1998, v.11 no.2, pp.88-91
You, Jae-Hoon
Lee, Sang-Ki
Jin, Kwang-Ho
In, Sang-Wban
Yoo, Young-Chan
Park, Sung-Woo
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Abstract

Bromide(<TEX>$Br^-$</TEX>) was separated and quantified with <TEX>$2.8mM-NaHCO_3/2.2mM-Na_2CO_3$</TEX> by Ion Chromatography. Bromide was eluted at 8.9 min. and the detectetion limit was 2.5 ng. We compared with bromide concentration in normal or methylbromide intoxicated bloods and tissues. Bromide concentrations were 2.0~5.8 ppm in normal bloods and 1.0~5.3 ppm in normal tissues. In fatal cases of methylbromide intoxication, blood bromide concentrations (4 cases) of 74.2~139 ppm and tissue bromide concentration (1 case) of 76 (heart)~201 (lung) ppm were detected. In fatal cases, blood bromide concentrations. were 12~22 times higher than those of normal bloods.

keywords
methylbromide, bromide concentration, blood, tissue


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