- P-ISSN 1225-0163
- E-ISSN 2288-8985
- Apply for Authority
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
Article Detail
Home > Article Detail
Optimization of analytical conditions for the determination of nitrosamines in chlorinated tap water by high performance liquid chromatography
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2010, v.23 no.6, pp.551-559
https://doi.org/10.5806/AST.2010.23.6.551
&
(2010). Optimization of analytical conditions for the determination of nitrosamines in chlorinated tap water by high performance liquid chromatography. Analytical Science and Technology, 23(6), 551-559, https://doi.org/10.5806/AST.2010.23.6.551
- Downloaded
- Viewed
Abstract
This study was conducted to establish an analytical method for the determination of seven nitrosamines in chlorinated tap water by precolumn derivatization followed by high performance liquid chromatography coupled with fluorescence detection. The derivatization procedure was optimized for denitrosation and dansylation, and then two extraction methods, liquid-liquid extraction (LLE) with dichloromethane and solid phase extraction (SPE), were compared. The SPE method employing the optimized derivation procedure showed higher extraction recovery (54.4-88.7%) and reproducibility (1.9-19.4%) than the LLE method (51.4-87.7% and 4.2-33.3%, respectively). The method detection limits were between 0.5 and 4.4 ng/L. When chlorinated water samples were collected from two treatment plants and ten household taps, and analyzed for nitrosamines, Nnitrosodimethylamine (NDMA) was the major compound found between 26.1 and 112 ng/L.
- keywords
- chlorinated tap water, dansylation, HPLC, nitrosamines, solid-phase extraction
Reference
1
1. International Agency for Research on Cancer (IARC). “IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans: Some N-nitroso compounds”, 1978.
2
2. US EPA, Integrated Risk Information System, Office of Research and Development (ORP), National Center for Environmental Assessment, http://www.epa.gov/iris.
3
3. J. E. Graham, S. A. Andrews, G. J. Farquhar and O. Meresz, Water quality technology conference, AWWA, New Orleans, LA, pp. 757-772(1995).
4
4. I. Najm and R. R. Trussell, J. Am. Water Works Assoc. 93, 92-99(2001).
5
5. J. Choi and R. L. Valentine, Water Res. 36, 817-824(2002).
6
6. A. C. Gerecke and D. L. Sedlak, Environ. Sci. Technol. 37, 1331-1336(2003).
7
7. W. A. Mitch and D. L. Sedlak, Environ. Sci. Technol. 36, 588-595(2002).
8
8. California Department of Health and Services, “NDMA in California Drinking Water”, http://www/dhs.ca.gov/ ddwem.chemiclas/NDMA/history.htm.
9
9. W. Mitch, J. Sharp, R. Trussell, R. Valentine, L. Alvarez- Cohen and D. Sedlak, Environ. Eng. Sci., 20, 389-404 (2003).
10
10. US EPA, “Determination of nitrosamines in drinking water by solid phase extraction and capillary column gas chromatography with large volume injection and chemical ionization tandem mass spectrometry (MS/ MS)”, U.S. EPA Method 521, 2004.
11
11. S. W. D. Jenkins, C. J. Koester, V. Y. Taguchi, D. T. Wang, J.-P. F. P. Palmentier and K. P. Hong, Environ. Sci. Pollut. Res. 2, 207-210(1995).
12
12. W. S. Cha, P. Fox and B. Nalinakumari, Analytica Chimica Acta., 566, 109-116(2006).
13
13. J. W. A. Charrois, M. W. Arend, K. L. Froese and S. E. Hrudey, Environ. Sci. Technol., 38, 4835-4841(2004).
14
14. Y.-Y. Zhao, J. Boyd, S. E. Hrudey and X.-F. Li, Environ. Sci. Technol., 40, 7636-7641(2006).
15
15. R. C. Cheng, C. Andrews-Tate, C. J. Hwang, Y. Guo, J. E. Gredel and I. H. Suffet, Water Quality Technology Conference Proceedings, American Water Works Association, Denver, CO., 2004.
16
16. S. S. Hecht, R. M. Ornaf and D. Hoffmann, Anal. Chem. 47, 2046-2048(1975).
17
17. Z. Wang, H. Xu and C. Fu, J. Chromatogr, 589, 349- 352(1992).
18
18. N. V. Komarova and A. A. Velikanov, Anal. Chem., 56(4), 359-363(2001).
19
19. J. W. A. Charrios, J. M. Boyd, K. L. Froese and S. E. Hrudey, J. Environ. Eng. Sci., 6, 103-114(2007).
Other articles from this issue
- Dissolution of vanadium pentoxide using microwave digestion system for determination of vanadium by ICP-AES
- A study on the analysis of uranium isotopes in environmental samples using a kinetic phosphorescence analyzer
- Accurate determination of chloramphenicol in meat by isotope dilution liquid chromatography mass spectrometry (ID-LC/MS)
- Quantitative determination of inosine 5’-monophosphate dehydrogenase activity in human peripheral blood mononuclear cells by ion-pair reversed-phase high-performance liquid chromatography
- Bioconjugation by dual heterobifunctional coupling method:Use of the conjugates for the detection of dopamine
- Simultaneous analysis of ethylene glycol and glycolic acid in bio-specimens by GC/MS
- Optimization of analytical conditions for the determination of nitrosamines in chlorinated tap water by high performance liquid chromatography
- Reduction of perchlorate in aqueous solution using zero valence iron stabilized with alginate bead
- Sorption of aqueous uranium(VI) ion onto a cation-exchangeable K-birnessite colloid
- Simultaneous analysis and occurrences of six pharmaceuticals in surface water by LC/ESI-MS/MS
- Antitumor agents bound to silica nanoparticles : potential technology for the remediation of malignant tumors
- Analytical method validation of oxiracetam using HPLC
- Exposure assessment of dioxins through foods
- A study on shape changes of hangul signature under the influence of alcohol
- Analysis of heavy metal in polymer materials by combustion ICP-AES Method
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.